U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C22H29FN3O9P
Molecular Weight 529.4525
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Fosclevudine Alafenamide

SMILES

CC(C)OC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1O[C@@H]([C@H](F)[C@H]1O)N2C=C(C)C(=O)NC2=O)OC3=CC=CC=C3

InChI

InChIKey=FTMNZJASLMPPNW-MHFVGYLCSA-N
InChI=1S/C22H29FN3O9P/c1-12(2)33-21(29)14(4)25-36(31,35-15-8-6-5-7-9-15)32-11-16-18(27)17(23)20(34-16)26-10-13(3)19(28)24-22(26)30/h5-10,12,14,16-18,20,27H,11H2,1-4H3,(H,25,31)(H,24,28,30)/t14-,16-,17+,18-,20-,36-/m0/s1

HIDE SMILES / InChI

Approval Year

Name Type Language
Fosclevudine Alafenamide
INN  
Official Name English
AT-2173
Code English
ATI-2173
Code English
fosclevudine alafenamide [INN]
Common Name English
L-ALANINE, N-((S)-HYDROXYPHENOXYPHOSPHINYL)-, 1-METHYLETHYL ESTER, 5'-ESTER WITH 1-(2-DEOXY-2-FLUORO-.BETA.-L-ARABINOFURANOSYL)-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE
Systematic Name English
propan-2-yl N-[(P5'S)-2'-deoxy-2'-fluoro-5-methyl-OPphenyl- β-L-arabino-5'-uridylyl]-L-alaninate
Common Name English
Code System Code Type Description
INN
12238
Created by admin on Sat Dec 16 16:06:32 GMT 2023 , Edited by admin on Sat Dec 16 16:06:32 GMT 2023
PRIMARY
FDA UNII
77AP23J0GH
Created by admin on Sat Dec 16 16:06:32 GMT 2023 , Edited by admin on Sat Dec 16 16:06:32 GMT 2023
PRIMARY
CAS
1951476-79-1
Created by admin on Sat Dec 16 16:06:32 GMT 2023 , Edited by admin on Sat Dec 16 16:06:32 GMT 2023
PRIMARY
PUBCHEM
147565559
Created by admin on Sat Dec 16 16:06:32 GMT 2023 , Edited by admin on Sat Dec 16 16:06:32 GMT 2023
PRIMARY
SMS_ID
300000043563
Created by admin on Sat Dec 16 16:06:32 GMT 2023 , Edited by admin on Sat Dec 16 16:06:32 GMT 2023
PRIMARY
NCI_THESAURUS
C190347
Created by admin on Sat Dec 16 16:06:32 GMT 2023 , Edited by admin on Sat Dec 16 16:06:32 GMT 2023
PRIMARY