U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C10H15NO.H2O4S
Molecular Weight 263.311
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RACEPHEDRINE SULFATE

SMILES

OS(O)(=O)=O.CN[C@H](C)[C@@H](O)C1=CC=CC=C1

InChI

InChIKey=XVPDSDYVNYOVMP-GHXDPTCOSA-N
InChI=1S/C10H15NO.H2O4S/c1-8(11-2)10(12)9-6-4-3-5-7-9;1-5(2,3)4/h3-8,10-12H,1-2H3;(H2,1,2,3,4)/t8-,10-;/m1./s1

HIDE SMILES / InChI
Racephedrine in combination with theophylline, phenobarbital was used to treat bronchial asthma. However, its application was substituted more effective agent. In addition, FDA has reviewed the final monograph for over-the-counter bronchodilator drug products to add additional warnings and to revise the indications in the labeling of products containing racephedrine hydrochloride.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Unknown

Approved Use

Unknown
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
79.4 ng/mL
22 mg single, oral
dose: 22 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
EPHEDRINE plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: UNKNOWN
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
751 ng × h/mL
22 mg single, oral
dose: 22 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
EPHEDRINE plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: UNKNOWN
food status: UNKNOWN
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
6.75 h
22 mg single, oral
dose: 22 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
EPHEDRINE plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: UNKNOWN
food status: UNKNOWN
PubMed

PubMed

TitleDatePubMed
[Delayed-action effect of a racephedrine, theophylline and phenobarbital combination on asthma. Study on 100 cases].
1968 Jul-Aug
Patents

Patents

Sample Use Guides

Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
RACEPHEDRINE SULFATE
Common Name English
BENZENEMETHANOL, .ALPHA.-(1-(METHYLAMINO)ETHYL)-, (R*,S*)-, SULFATE (2:1) (SALT)
Systematic Name English
(1RS,2SR)-2-(METHYLAMINO)-1-PHENYLPROPAN-1-OL SULFATE
Systematic Name English
DL-EPHEDRINE SULFATE
Common Name English
RACEPHEDRINE MONOSULFATE
Common Name English
EPHEDRINE SULFATE, DL
Common Name English
Code System Code Type Description
CAS
154-45-0
Created by admin on Sat Dec 16 00:42:12 GMT 2023 , Edited by admin on Sat Dec 16 00:42:12 GMT 2023
PRIMARY
FDA UNII
730X185N08
Created by admin on Sat Dec 16 00:42:12 GMT 2023 , Edited by admin on Sat Dec 16 00:42:12 GMT 2023
PRIMARY
EPA CompTox
DTXSID40934890
Created by admin on Sat Dec 16 00:42:12 GMT 2023 , Edited by admin on Sat Dec 16 00:42:12 GMT 2023
PRIMARY
PUBCHEM
20111738
Created by admin on Sat Dec 16 00:42:12 GMT 2023 , Edited by admin on Sat Dec 16 00:42:12 GMT 2023
PRIMARY
ECHA (EC/EINECS)
205-828-8
Created by admin on Sat Dec 16 00:42:12 GMT 2023 , Edited by admin on Sat Dec 16 00:42:12 GMT 2023
PRIMARY