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Details

Stereochemistry RACEMIC
Molecular Formula C11H12NO3.Na
Molecular Weight 229.2076
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AFALANINE SODIUM

SMILES

[Na+].CC(=O)NC(CC1=CC=CC=C1)C([O-])=O

InChI

InChIKey=RBMBEFVVHHNLAR-UHFFFAOYSA-M
InChI=1S/C11H13NO3.Na/c1-8(13)12-10(11(14)15)7-9-5-3-2-4-6-9;/h2-6,10H,7H2,1H3,(H,12,13)(H,14,15);/q;+1/p-1

HIDE SMILES / InChI

Description
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/7340854

AFALANINE was developed by Medea Research in Italy and licensed to Pulitzer. Phase III clinical trials of MR 708 were completed by Pulitzer. Antidepressant; Antiparkinsonian; Neuroprotectant; Nootropic, Dopamine receptor agonist, was used to treat Major depressive disorder.

Originator

Curator's Comment: AFALANINE was developed by Medea Research in Italy and licensed to Pulitzer.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Digestive proteolytic activity in the Sunn pest, Eurygaster integriceps.
2009
Genetic algorithms as a tool for capillary electrophoresis method development.
2002
[Isolation and characteristics of immobilized aminoacylase from Streptoverticillium olivoreticuli].
2001-03-10
Patents

Sample Use Guides

Dogs/rats - AFALANINE (MR-708) produced a mild and transienth hypertension when given to narcotized dogs at the dosage rate of 4.5 mg/kg, and to rats narcotized by bilateral vagotomy at the dosage rate of 5 mg/kg
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
AFALANINE SODIUM SALT
Preferred Name English
AFALANINE SODIUM
Common Name English
DL-N-ACETYLPHENYLALANINE SODIUM SALT
Common Name English
N-ACETYLPHENYLALANINE SODIUM, (±)-
Systematic Name English
N-ACETYLPHENYLALANINE SODIUM, DL-
Common Name English
Code System Code Type Description
FDA UNII
6Z92N83B5U
Created by admin on Mon Mar 31 22:02:56 GMT 2025 , Edited by admin on Mon Mar 31 22:02:56 GMT 2025
PRIMARY
PUBCHEM
23686419
Created by admin on Mon Mar 31 22:02:56 GMT 2025 , Edited by admin on Mon Mar 31 22:02:56 GMT 2025
PRIMARY
CAS
74407-30-0
Created by admin on Mon Mar 31 22:02:56 GMT 2025 , Edited by admin on Mon Mar 31 22:02:56 GMT 2025
PRIMARY