Details
Stereochemistry | RACEMIC |
Molecular Formula | C11H12NO3.Na |
Molecular Weight | 229.2076 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].CC(=O)NC(CC1=CC=CC=C1)C([O-])=O
InChI
InChIKey=RBMBEFVVHHNLAR-UHFFFAOYSA-M
InChI=1S/C11H13NO3.Na/c1-8(13)12-10(11(14)15)7-9-5-3-2-4-6-9;/h2-6,10H,7H2,1H3,(H,12,13)(H,14,15);/q;+1/p-1
DescriptionSources: http://adisinsight.springer.com/drugs/800003808Curator's Comment: Description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/7340854
Sources: http://adisinsight.springer.com/drugs/800003808
Curator's Comment: Description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/7340854
AFALANINE was developed by Medea Research in Italy and licensed to Pulitzer. Phase III clinical trials of MR 708 were completed by Pulitzer. Antidepressant; Antiparkinsonian; Neuroprotectant; Nootropic, Dopamine receptor agonist, was used to treat Major depressive disorder.
CNS Activity
Originator
Sources: http://adisinsight.springer.com/drugs/800003808
Curator's Comment: AFALANINE was developed by Medea Research in Italy and licensed to Pulitzer.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL2096905 Sources: http://adisinsight.springer.com/drugs/800003808 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Primary | Unknown Approved UseUnknown |
Sample Use Guides
In Vivo Use Guide
Sources: http://www.google.com/patents/CA1144162A?cl=en
Dogs/rats - AFALANINE (MR-708) produced a mild and transienth hypertension when given to narcotized dogs at the dosage rate of 4.5 mg/kg, and to rats narcotized by bilateral vagotomy at the dosage rate of 5 mg/kg
Route of Administration:
Unknown
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6Z92N83B5U
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admin on Sat Dec 16 08:23:52 GMT 2023 , Edited by admin on Sat Dec 16 08:23:52 GMT 2023
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23686419
Created by
admin on Sat Dec 16 08:23:52 GMT 2023 , Edited by admin on Sat Dec 16 08:23:52 GMT 2023
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74407-30-0
Created by
admin on Sat Dec 16 08:23:52 GMT 2023 , Edited by admin on Sat Dec 16 08:23:52 GMT 2023
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ACTIVE MOIETY
SUBSTANCE RECORD