| Stereochemistry | ABSOLUTE |
| Molecular Formula | C15H22O2 |
| Molecular Weight | 234.334 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12CC[C@H](C(O)=O)[C@@]13CC[C@H](C3)C(C)(C)C2=C
InChI
InChIKey=IJGMVUXEZUEDJR-RTWAVKEYSA-N
InChI=1S/C15H22O2/c1-9-11-4-5-12(13(16)17)15(11)7-6-10(8-15)14(9,2)3/h10-12H,1,4-8H2,2-3H3,(H,16,17)/t10-,11-,12-,15-/m1/s1
Zizanoic acid is a sesquiterpene in vetiver oil. Zizanoic acid exhibited significant antimycobacterial activity against drug-resistant mutants of M. smegmatis and virulent strain H37Rv of M. tuberculosis. These observations may be of great help in the QSAR-based antimycobacterial drug designing from a very common, inexpensive and non-toxic natural product for the management of MDR and XDR tuberculosis.
Originator
Approval Year
PubMed
Patents
SUBSTANCE RECORD
