Details
Stereochemistry | ACHIRAL |
Molecular Formula | C2HCl2F3 |
Molecular Weight | 152.931 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
FC(F)(F)C(Cl)Cl
InChI
InChIKey=OHMHBGPWCHTMQE-UHFFFAOYSA-N
InChI=1S/C2HCl2F3/c3-1(4)2(5,6)7/h1H
Approval Year
PubMed
Title | Date | PubMed |
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Metabolism of the chlorofluorocarbon substitute 1,1-dichloro-2,2,2-trifluoroethane by rat and human liver microsomes: the role of cytochrome P450 2E1. | 1994 Mar-Apr |
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Biotransformation and hepatotoxicity of HCFC-123 in the guinea pig: potentiation of hepatic injury by prior glutathione depletion. | 1995 Sep |
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Cytochrome P450 inactivation during reductive metabolism of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) by phenobarbital- and pyridine-induced rat liver microsomes. | 1997 Apr |
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Epidemic of liver disease caused by hydrochlorofluorocarbons used as ozone-sparing substitutes of chlorofluorocarbons. | 1997 Aug 23 |
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Potentiation of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123)-induced liver toxicity by ethanol in guinea-pigs. | 2002 Dec |
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Development of a sampling and analytical method for 2,2-dichloro-1,1,1-trifluoroethane in workplace air. | 2002 Nov-Dec |
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Hepatotoxicity associated with overexposure to 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123). | 2003 Jan-Feb |
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Quantitative structure-property relationships for physiologically based pharmacokinetic modeling of volatile organic chemicals in rats. | 2003 Jun 15 |
|
Trifluoroacetylated proteins in liver and plasma of guinea pigs treated with HCFC-123 and halothane. | 2003 Sep 15 |
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Code System | Code | Type | Description | ||
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2,2-Dichloro-1,1,1-trifluoroethane
Created by
admin on Fri Dec 15 15:16:37 GMT 2023 , Edited by admin on Fri Dec 15 15:16:37 GMT 2023
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PRIMARY | |||
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34077-87-7
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NON-SPECIFIC SUBSTITUTION | |||
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DTXSID7020712
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306-83-2
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6874
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9385
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206-190-3
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6S7C791U3V
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admin on Fri Dec 15 15:16:37 GMT 2023 , Edited by admin on Fri Dec 15 15:16:37 GMT 2023
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6874
Created by
admin on Fri Dec 15 15:16:37 GMT 2023 , Edited by admin on Fri Dec 15 15:16:37 GMT 2023
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ALTERNATIVE |
SUBSTANCE RECORD