1,1,1-TRIFLUORO-2,2-DICHLOROETHANE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2HCl2F3
Molecular Weight	152.931
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 1,1,1-TRIFLUORO-2,2-DICHLOROETHANE

Structure Search

SMILES

FC(F)(F)C(Cl)Cl

InChI

InChIKey=OHMHBGPWCHTMQE-UHFFFAOYSA-N

InChI=1S/C2HCl2F3/c3-1(4)2(5,6)7/h1H

HIDE SMILES / InChI

Molecular Formula	C2HCl2F3
Molecular Weight	152.931
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Gas-uptake pharmacokinetics of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123).	1994 Jul-Aug	7956723
Hepatotoxicity in guinea pigs following acute inhalation exposure to 1,1-dichloro-2,2,2-trifluoroethane.	1994 Jul-Aug	7817129
Metabolism of the chlorofluorocarbon substitute 1,1-dichloro-2,2,2-trifluoroethane by rat and human liver microsomes: the role of cytochrome P450 2E1.	1994 Mar-Apr	8199305
Two-year inhalation toxicity study in rats with hydrochlorofluorocarbon 123.	1995 Apr	7601319
Biotransformation and hepatotoxicity of HCFC-123 in the guinea pig: potentiation of hepatic injury by prior glutathione depletion.	1995 Sep	7676453
Bioactivation and cytotoxicity of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) in isolated rat hepatocytes.	2001 Apr	11322177
Cross-fostering inhalation toxicity study with HCFC-123 in lactating Sprague-Dawley rats.	2001 Aug	11498800
Investigations on the liver toxicity of a blend of HCFC-123 (2,2-dichloro-1,1,1-trifluoroethane) and HCFC-124 (2-chloro-1,1,1,2-tetrafluoroethane) in guinea-pigs.	2001 Jul	11548120
Bioactivation and toxicity in vitro of HCFC-123 and HCFC-141b: role of cytochrome P450.	2001 Oct 15	11684366
Neoantigen formation and clastogenic action of HCFC-123 and perchloroethylene in human MCL-5 cells.	2001 Oct 15	11684365
Selective inactivation of rat and bovine olfactory cytochrome P450 by three haloethanes.	2001 Oct 15	11684360
Potentiation of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123)-induced liver toxicity by ethanol in guinea-pigs.	2002 Dec	12451447
Effects of HCFC-123 exposure to maternal and infant rhesus monkeys on hepatic biochemistry, lactational parameters and postnatal growth.	2002 Nov	12378954
Development of a sampling and analytical method for 2,2-dichloro-1,1,1-trifluoroethane in workplace air.	2002 Nov-Dec	12570079
Hepatotoxicity associated with overexposure to 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123).	2003 Jan-Feb	12570398
Quantitative structure-property relationships for physiologically based pharmacokinetic modeling of volatile organic chemicals in rats.	2003 Jun 15	12791307
Reductive activation of HCFC-123 by methaemalbumin.	2003 Sep 15	12919730
Trifluoroacetylated proteins in liver and plasma of guinea pigs treated with HCFC-123 and halothane.	2003 Sep 15	12919722
Three-dimensional modeling of HCFC-123 in the atmosphere: assessing its potential environmental impacts and rationale for continued use.	2009 May 1	19534136

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:37 GMT 2023` Edited by `admin` on `Fri Dec 15 15:16:37 GMT 2023`
Record UNII	6S7C791U3V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,1,1-TRIFLUORO-2,2-DICHLOROETHANE

Systematic Name

English

SOLKANE 123

Brand Name

English

1,1,1-TRIFLUORODICHLOROETHANE

Systematic Name

English

2,2-DICHLORO-1,1,1-TRIFLUOROETHANE

Systematic Name

English

CFC-123

Code

English

KHLADON 123

Brand Name

English

HCFC-123

Code

English

ETHANE, 2,2-DICHLORO-1,1,1-TRIFLUORO-

Systematic Name

English

1,1-DICHLORO-2,2,2-TRIFLUOROETHANE

Systematic Name

English

FREON 123

Common Name

English

DICHLOROTRIFLUOROETHANE

Common Name

English

R 123

Common Name

English

DICHLORO(TRIFLUOROMETHYL)METHANE

Systematic Name

English

HFA-123

Code

English

DICHLOROTRIFLUOROETHANE [HSDB]

Common Name

English

Code System Code Type Description

WIKIPEDIA

2,2-Dichloro-1,1,1-trifluoroethane