Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H19N5O.ClH |
| Molecular Weight | 381.859 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CN(C(C)=O)C1=CC=C(NC2=C3C4=C(NC=N4)C=CC3=NC(C)=C2)C=C1
InChI
InChIKey=SOCGJDYHNGLZEC-UHFFFAOYSA-N
InChI=1S/C20H19N5O.ClH/c1-12-10-18(19-16(23-12)8-9-17-20(19)22-11-21-17)24-14-4-6-15(7-5-14)25(3)13(2)26;/h4-11H,1-3H3,(H,21,22)(H,23,24);1H
Acodazole is a synthetic imidazoquinoline with antimicrobial and antineoplastic activity. Acodazole intercalates into DNA, resulting in disruption of DNA replication. Use of this agent has been associated with significant cardiotoxicity, especially prolonged cardiac output interval (Q-Ti) on electrocardiogram and polymorphic ventricular tachycardia ("torsades des pointes").
Approval Year
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NCI_THESAURUS |
C582
Created by
admin on Mon Mar 31 18:24:54 GMT 2025 , Edited by admin on Mon Mar 31 18:24:54 GMT 2025
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CHEMBL188427
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55435-65-9
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305884
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T-33
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DTXSID40204000
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6D7W9EAH22
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300000055009
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5361207
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C71627
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ACTIVE MOIETY
SUBSTANCE RECORD
