Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C17H15BrN2 |
| Molecular Weight | 327.218 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
BrC1=CC=C(C=C1)C(CN2C=CN=C2)C3=CC=CC=C3
InChI
InChIKey=MLHFXOOXBZMGSH-UHFFFAOYSA-N
InChI=1S/C17H15BrN2/c18-16-8-6-15(7-9-16)17(12-20-11-10-19-13-20)14-4-2-1-3-5-14/h1-11,13,17H,12H2
Brolaconazole is imidazole derivative with potent antimicrobial activity against pathogenic fungi, molds, yeasts, and Gram-positive bacteria. Brolaconazole showed an inhibition band of 20-40 mM against Candida albican and it demonstrates higher activity compare bifonazole. Brolaconazole is useful for the treatment of dermal and vaginal infections such as vaginal candidiasis, tinea corporis, tinea pedis, tinea cruris, and other dermal infections.
Approval Year
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NCI_THESAURUS |
C514
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DTXSID10276693
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6203
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CHEMBL2104202
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189880
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C72957
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100000088668
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108894-40-2
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118528-04-4
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SUB05902MIG
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6CHG505391
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ACTIVE MOIETY
