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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H27NO3
Molecular Weight 317.4226
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TETRABENAZINE, (+)-

SMILES

[H][C@]12CC(=O)[C@H](CC(C)C)CN1CCC3=CC(OC)=C(OC)C=C23

InChI

InChIKey=MKJIEFSOBYUXJB-GDBMZVCRSA-N
InChI=1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/m1/s1

HIDE SMILES / InChI

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Synaptic vesicular amine transporter
57
Target ID: Q05940
Gene ID: 6571.0
Gene Symbol: SLC18A2
Target Organism: Homo sapiens (Human)
Inhibitor
8297
 36400.0 nM [Ki]
PubMed

PubMed

TitleDatePubMed
Tetrabenazine in the treatment of Huntington's disease.
2007
Patents

Patents

JPH02282307A
1
Name Type Language
TETRABENAZINE, (+)-
Common Name English
(+)-TBZ
Common Name English
TETRABENAZINE R,R-FORM [MI]
Common Name English
(+)-TETRABENAZINE
Common Name English
(3R,11BR)-TBZ
Common Name English
2H-BENZO(A)QUINOLIZIN-2-ONE, 1,3,4,6,7,11B-HEXAHYDRO-9,10-DIMETHOXY-3-(2-METHYLPROPYL)-, (3R,11BR)-
Systematic Name English
(3R,11BR)-1,3,4,6,7,11B-HEXAHYDRO-9,10-DIMETHOXY-3-(2-METHYLPROPYL)-2H-BENZO(A)QUINOLIZIN-2-ONE
Systematic Name English
(3R,11BR)-TETRABENAZINE
Common Name English
Code System Code Type Description
MERCK INDEX
m10596
Created by admin on Sat Dec 16 08:54:11 UTC 2023 , Edited by admin on Sat Dec 16 08:54:11 UTC 2023
PRIMARY Merck Index
EPA CompTox
DTXSID101117156
Created by admin on Sat Dec 16 08:54:11 UTC 2023 , Edited by admin on Sat Dec 16 08:54:11 UTC 2023
PRIMARY
FDA UNII
69ENL3U6BF
Created by admin on Sat Dec 16 08:54:11 UTC 2023 , Edited by admin on Sat Dec 16 08:54:11 UTC 2023
PRIMARY
PUBCHEM
667453
Created by admin on Sat Dec 16 08:54:11 UTC 2023 , Edited by admin on Sat Dec 16 08:54:11 UTC 2023
PRIMARY
CAS
1026016-83-0
Created by admin on Sat Dec 16 08:54:11 UTC 2023 , Edited by admin on Sat Dec 16 08:54:11 UTC 2023
PRIMARY
CHEBI
64029
Created by admin on Sat Dec 16 08:54:11 UTC 2023 , Edited by admin on Sat Dec 16 08:54:11 UTC 2023
PRIMARY
SUBSTANCE RECORD
Structure of TETRABENAZINE, (+)-
NIH
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