Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H5O4P.2Na |
| Molecular Weight | 218.0548 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[Na+].[O-]P([O-])(=O)OC1=CC=CC=C1
InChI
InChIKey=TYJOJLOWRIQYQM-UHFFFAOYSA-L
InChI=1S/C6H7O4P.2Na/c7-11(8,9)10-6-4-2-1-3-5-6;;/h1-5H,(H2,7,8,9);;/q;2*+1/p-2
Disodium phenyl phosphate is a monophenyl ester of phosphoric acid. It is used as tool compound to study the efficacy of phosphatases. Hydrolysis of phenyl phosphate by milk phosphatases was used to used to indicate whether milk has been adequately pasteurized or whether it has been contaminated with raw milk after pasteurization. Phenyl phosphate was also used as a molecular fragment for fragment-based drug discovery of Src SH2.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Cloning and characterization of a second acid phosphatase from Sinorhizobium meliloti strain 104A14. | 2001 Oct |
|
| Comparative study of bis(benzyl)phosphate triesters of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T) and cyclosal-d4TMP--hydrolysis, mechanistic insights and anti-HIV activity. | 2002 Mar |
|
| Effects of some trivalent metal ions on the fluoride-induced chemiluminescence from a phenylphosphate-substituted dioxetane Lumigen PPD. | 2002 Sep-Oct |
|
| Structure-based design of novel nonpeptide inhibitors of the Src SH2 domain:phosphotyrosine mimetics exploiting multifunctional group replacement chemistry. | 2003 |
|
| The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase. | 2003 May 7 |
|
| Recognition of phosphate monoester dianion by an alkoxide-bridged dinuclear zinc(II) complex. | 2004 Apr 21 |
|
| Kinetic and structural consequences of the leaving group in substrates of a class C beta-lactamase. | 2004 Mar 15 |
|
| Positive cooperativity in substrate binding of human prostatic acid phosphatase entrapped in AOT-isooctane-water reverse micelles. | 2004 May 15 |
|
| Inhibitors for proteins endowed with catalytic and non-catalytic activity which recognize pTyr. | 2004 Oct |
|
| Hydroquinone diphosphate: an alkaline phosphatase substrate that does not produce electrode fouling in electrochemical immunoassays. | 2004 Sep 15 |
|
| Cooperation between artificial receptors and supramolecular hydrogels for sensing and discriminating phosphate derivatives. | 2005 Aug 24 |
|
| Rapid and highly sensitive electrochemical determination of alkaline phosphatase using a composite tyrosinase biosensor. | 2005 Jan 15 |
|
| Column selection and method development for the separation of nucleoside phosphotriester diastereoisomers, new potential anti-viral drugs. Application to cellular extract analysis. | 2005 Jul |
|
| Specific determination of As(V) by an acid phosphatase-polyphenol oxidase biosensor. | 2006 Jul 15 |
|
| A phage antibody to the active site of human placental alkaline phosphatase with higher affinity to the enzyme-substrate complex. | 2007 Jan |
|
| Anticancer alkaloid lamellarins inhibit protein kinases. | 2008 |
|
| A review of current intravaginal drug delivery approaches employed for the prophylaxis of HIV/AIDS and prevention of sexually transmitted infections. | 2008 |
|
| Immunosensor for the determination of Staphylococcus aureus using a tyrosinase-mercaptopropionic acid modified electrode as an amperometric transducer. | 2008 Jun |
Sample Use Guides
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221-917-4
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m4669
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3279-54-7
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76771
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DTXSID10889429
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7190
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682542868D
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SUBSTANCE RECORD
