Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H5O4P.2Na |
| Molecular Weight | 218.0548 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[Na+].[O-]P([O-])(=O)OC1=CC=CC=C1
InChI
InChIKey=TYJOJLOWRIQYQM-UHFFFAOYSA-L
InChI=1S/C6H7O4P.2Na/c7-11(8,9)10-6-4-2-1-3-5-6;;/h1-5H,(H2,7,8,9);;/q;2*+1/p-2
| Molecular Formula | C6H5O4P |
| Molecular Weight | 172.0753 |
| Charge | -2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.98976928 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Disodium phenyl phosphate is a monophenyl ester of phosphoric acid. It is used as tool compound to study the efficacy of phosphatases. Hydrolysis of phenyl phosphate by milk phosphatases was used to used to indicate whether milk has been adequately pasteurized or whether it has been contaminated with raw milk after pasteurization. Phenyl phosphate was also used as a molecular fragment for fragment-based drug discovery of Src SH2.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase. | 2010-12-14 |
|
| Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets. | 2010-12-01 |
|
| Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling. | 2010-11-10 |
|
| Biochemical and histologic changes in rats after prolonged administration of the crude aqueous extract of the leaves of Vitex grandifolia. | 2010-09 |
|
| Immobilization of enzymes at high load/activity by aqueous electrodeposition of enzyme-tethered chitosan for highly sensitive amperometric biosensing. | 2010-08-15 |
|
| Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models. | 2010-08-12 |
|
| Hydrogen bonding in phosphine oxide/phosphate-phenol complexes. | 2010-07-12 |
|
| Comparative theoretical studies of the phosphomonoester hydrolysis mechanism by purple acid phosphatases. | 2010-07-08 |
|
| The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis. | 2010-05-26 |
|
| Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation. | 2010-03-19 |
|
| Stoichiometry and intracellular fate of TRIM-containing TCR complexes. | 2010-03-18 |
|
| Chemoprotective Effect of Sobatum against Lithium-Induced Oxidative Damage in Rats. | 2010-01 |
|
| A highly sensitive enzyme-amplified immunosensor based on a nanoporous niobium oxide (Nb2O5) electrode. | 2010 |
|
| EEVD motif of heat shock cognate protein 70 contributes to bacterial uptake by trophoblast giant cells. | 2009-12-15 |
|
| Inhibition of rat Na+(-)HCO3(-) cotransporter (NBCn1) function and expression by the alternative splice domain. | 2009-11 |
|
| [Comparative-enzymologic study of phosphatase activity of hydrobionts from Pacific Ocean]. | 2009-09-22 |
|
| Enhanced bactericidal activity of enterocin AS-48 in combination with essential oils, natural bioactive compounds and chemical preservatives against Listeria monocytogenes in ready-to-eat salad. | 2009-09 |
|
| Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB: indications of a surprisingly complex life-style and cryptic anaerobic pathways for aromatic degradation. | 2009-08-03 |
|
| Ultrasensitive electrochemical DNA assay based on counting of single magnetic nanobeads by a combination of DNA amplification and enzyme amplification. | 2009-03-01 |
|
| The trefoil factor interacting protein TFIZ1 binds the trefoil protein TFF1 preferentially in normal gastric mucosal cells but the co-expression of these proteins is deregulated in gastric cancer. | 2009-03 |
|
| Determination of lactoferrin and immunoglobulin g in animal milks by new immunosensors. | 2009 |
|
| The detection of alkaline phosphatase using an electrochemical biosensor in a single-step approach. | 2009 |
|
| Immobilization of enzymes through one-pot chemical preoxidation and electropolymerization of dithiols in enzyme-containing aqueous suspensions to develop biosensors with improved performance. | 2008-08-01 |
|
| A DFT study on the formation of a phosphohistidine intermediate in prostatic acid phosphatase. | 2008-07-30 |
|
| Immunosensor for the determination of Staphylococcus aureus using a tyrosinase-mercaptopropionic acid modified electrode as an amperometric transducer. | 2008-06 |
|
| Heparin inhibits osteoclastic differentiation and function. | 2008-04-15 |
|
| Mutational analysis of betaCOP (Sec26p) identifies an appendage domain critical for function. | 2008-01-22 |
|
| Time-resolved fluorescence-based assay for the determination of alkaline phosphatase activity and application to the screening of its inhibitors. | 2008-01 |
|
| Anticancer alkaloid lamellarins inhibit protein kinases. | 2008 |
|
| Identification of a Novel Regulator for the Escherichia coli fit Iron Transport System. | 2008 |
|
| A review of current intravaginal drug delivery approaches employed for the prophylaxis of HIV/AIDS and prevention of sexually transmitted infections. | 2008 |
|
| [Semen biochemical markers and their significance in the patients with premature ejaculation]. | 2007-12 |
|
| [Specific recognition and detection of phosphorylated proteins using characteristics of metal ion]. | 2007-12 |
|
| Evaluation of titanium and titanium oxides as chemo-affinity sorbents for the selective enrichment of organic phosphates. | 2007-11 |
|
| Nanostructured progesterone immunosensor using a tyrosinase-colloidal gold-graphite-Teflon biosensor as amperometric transducer. | 2007-07-16 |
|
| A highly sensitive assay for monitoring the secretory pathway and ER stress. | 2007-06-27 |
|
| A phage antibody to the active site of human placental alkaline phosphatase with higher affinity to the enzyme-substrate complex. | 2007-01 |
|
| Theoretical evaluation of the substrate-assisted catalysis mechanism for the hydrolysis of phosphate monoester dianions. | 2007 |
|
| Free-energy profiles for catalysis by dual-specificity phosphatases. | 2006-10-15 |
|
| Specific determination of As(V) by an acid phosphatase-polyphenol oxidase biosensor. | 2006-07-15 |
|
| Urea-, thiourea-, and guanidine-linked glycooligomers as phosphate binders in water. | 2006-07-07 |
|
| Monitoring yoctomole alkaline phosphatase by capillary electrophoresis with on-capillary catalysis-electrochemical detection. | 2006-06-30 |
|
| Nano-titanium dioxide composites for the enrichment of phosphopeptides. | 2006-05-26 |
|
| An 18 kDa acid phosphatase from chicken heart possesses phosphotransferase activity. | 2006-02 |
|
| Effect of connective tissue growth factor (CCN2/CTGF) on proliferation and differentiation of mouse periodontal ligament-derived cells. | 2005-10-05 |
|
| Unusual reactions involved in anaerobic metabolism of phenolic compounds. | 2005-10 |
|
| Cooperation between artificial receptors and supramolecular hydrogels for sensing and discriminating phosphate derivatives. | 2005-08-24 |
|
| Thiolysis and alcoholysis of phosphate tri- and monoesters with alkyl and aryl leaving groups. An ab initio study in the gas phase. | 2005-06-30 |
|
| Study of ion exchange selectivity of organic ions by using (31)P NMR spectroscopy. | 2003-02-06 |
|
| Continuous assay for acid phosphatase using phenyl phosphate. | 1996-10-15 |
Sample Use Guides
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:09:31 GMT 2025
by
admin
on
Mon Mar 31 21:09:31 GMT 2025
|
| Record UNII |
682542868D
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
221-917-4
Created by
admin on Mon Mar 31 21:09:31 GMT 2025 , Edited by admin on Mon Mar 31 21:09:31 GMT 2025
|
PRIMARY | |||
|
m4669
Created by
admin on Mon Mar 31 21:09:31 GMT 2025 , Edited by admin on Mon Mar 31 21:09:31 GMT 2025
|
PRIMARY | Merck Index | ||
|
3279-54-7
Created by
admin on Mon Mar 31 21:09:31 GMT 2025 , Edited by admin on Mon Mar 31 21:09:31 GMT 2025
|
PRIMARY | |||
|
76771
Created by
admin on Mon Mar 31 21:09:31 GMT 2025 , Edited by admin on Mon Mar 31 21:09:31 GMT 2025
|
PRIMARY | |||
|
DTXSID10889429
Created by
admin on Mon Mar 31 21:09:31 GMT 2025 , Edited by admin on Mon Mar 31 21:09:31 GMT 2025
|
PRIMARY | |||
|
7190
Created by
admin on Mon Mar 31 21:09:31 GMT 2025 , Edited by admin on Mon Mar 31 21:09:31 GMT 2025
|
PRIMARY | |||
|
682542868D
Created by
admin on Mon Mar 31 21:09:31 GMT 2025 , Edited by admin on Mon Mar 31 21:09:31 GMT 2025
|
PRIMARY |