TEOPRANITOL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C16H22N6O7
Molecular Weight	410.3819
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12OC[C@H](O[N+]([O-])=O)[C@@]1([H])OC[C@@H]2NCCCN3C=NC4=C3C(=O)N(C)C(=O)N4C

InChI

InChIKey=XTEGRRHNMFDROI-YRRQLQLVSA-N

InChI=1S/C16H22N6O7/c1-19-14-11(15(23)20(2)16(19)24)21(8-18-14)5-3-4-17-9-6-27-13-10(29-22(25)26)7-28-12(9)13/h8-10,12-13,17H,3-7H2,1-2H3/t9-,10-,12+,13+/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3732290 | https://www.ncbi.nlm.nih.gov/pubmed/3137069 | https://adisinsight.springer.com/drugs/800000168

Teopranitol, a coronary vasodilator that was studied for the treatment of the acute myocardial ischemia. Animal experiments have shown that this compound stimulated the release of prostacyclin (PGI2)-like antiplatelet activity. However, the development of teopranitol was discontinued.

Originator

Approval Year

PubMed

Title	Date	PubMed
Stimulation of coronary vascular PGI2 by organic nitrates.	1988 Jan	3137069

Name

Type

Language

TEOPRANITOL

Official Name

English

teopranitol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707