U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C22H28N2O3
Molecular Weight 368.4693
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHOXYFENOZIDE

SMILES

COC1=C(C)C(=CC=C1)C(=O)NN(C(=O)C2=CC(C)=CC(C)=C2)C(C)(C)C

InChI

InChIKey=QCAWEPFNJXQPAN-UHFFFAOYSA-N
InChI=1S/C22H28N2O3/c1-14-11-15(2)13-17(12-14)21(26)24(22(4,5)6)23-20(25)18-9-8-10-19(27-7)16(18)3/h8-13H,1-7H3,(H,23,25)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
The chemical and biological properties of methoxyfenozide, a new insecticidal ecdysteroid agonist.
2001 Feb
Significance of absorption, oxidation, and binding to toxicity of four ecdysone agonists in multi-resistant cotton leafworm.
2001 Mar
Resistance and cross-resistance to four insecticides in populations of obliquebanded leafroller (Lepidoptera: Tortricidae).
2002 Aug
Inhibition of [3H]ponasterone A binding by ecdysone agonists in the intact Kc cell line.
2002 Feb
The multicolored Asian lady beetle, Harmonia axyridis: a review of its biology, uses in biological control, and non-target impacts.
2003
Ecdysone agonists: mechanism and importance in controlling insect pests of agriculture and forestry.
2003 Dec
Effects of methoxyfenozide-treated surfaces on the attractiveness and responsiveness of adult codling moth (Lepidoptera: Tortricidae).
2003 Jun
Effect of ecdysone agonists on vitellogenesis and the expression of EcR and USP in codling moth (Cydia pomonella).
2003 Mar
Toxicity and kinetics of methoxyfenozide in greenhouse-selected Spodoptera exigua (Lepidoptera: Noctuidae).
2003 Nov
Incidence and control of dogwood borer (Lepidoptera: Sesiidae) and American plum borer (Lepidoptera: Pyralidae) infesting burrknots on clonal apple rootstocks in New York.
2004 Apr
Effects of two biorational insecticides, spinosad and methoxyfenozide, on Spodoptera littoralis (Lepidoptera: Noctuidae) under laboratory conditions.
2004 Dec
Nonsteroidal ecdysone agonists.
2005
Role of neonicotinyl insecticides in Washington apple integrated pest management. Part I. Control of lepidopteran pests.
2005
Development, oviposition, and mortality of Neoseiulus fallacis (Acari: Phytoseiidae) in response to reduced-risk insecticides.
2005 Dec
Classical and three-dimensional QSAR for the inhibition of [3H]ponasterone A binding by diacylhydrazine-type ecdysone agonists to insect Sf-9 cells.
2005 Feb 15
Side effects of conventional and non-conventional insecticides on eggs and larvae of Chrysoperla externa (Hagen) (Neuroptera: Chrysopidae) in Argentine.
2006
Efficacy of some plant oils alone and/or combined with different insecticides on the cotton leaf-worm Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae) in Egypt.
2006
Bumblebees can be used in combination with juvenile hormone analogues and ecdysone agonists.
2006 Aug
Tebufenozide resistance selected in Plutella xylostella and its cross-resistance and fitness cost.
2006 Aug
Development of a methoxyfenozide-responsive gene switch for applications in plants.
2006 Feb
Cathepsin B-like proteinase is involved in the decomposition of the adult fat body of Helicoverpa armigera.
2006 May
Laboratory studies to elucidate the residual toxicity of eight insecticides to Anystis baccarum (Acari: Anystidae).
2007 Aug
Novel life stage targets against plum curculio, Conotrachelus nenuphar (Herbst), in apple integrated pest management.
2007 Aug
Sublethal exposure to methoxyfenozide-treated surfaces reduces the attractiveness and responsiveness in adult oriental fruit moth (Lepidoptera: Tortricidae).
2007 Feb
QSAR and mode of action studies of insecticidal ecdysone agonists.
2007 Jan-Mar
Lethal and sublethal effects of methoxyfenozide and spinosad on Spodoptera littoralis (Lepidoptera: Noctuidae).
2007 Jun
Development of a tightly regulated and highly inducible ecdysone receptor gene switch for plants through the use of retinoid X receptor chimeras.
2007 Oct
The ecological impact of four IGR insecticides in adults of Hyposoter didymator (Hym., Ichneumonidae): pharmacokinetics approach.
2008 Apr
Susceptibility of Chrysoperla externa eggs (Neuroptera: Chrisopidae) to conventional and biorational insecticides.
2008 Oct
Effects of classical insect hormones on the expression profiles of a lipase gene from the cotton bollworm (Helicoverpa armigera).
2008 Sep
Ecdysteroid signaling in ecdysteroid-resistant cell lines from the polyphagous noctuid pest Spodoptera exigua.
2008 Sep
Control of grape berry moth (Lepidoptera: Tortricidae) in relation to oviposition phenology.
2009 Apr
N'-Benzoyl-N-tert-butyl-2-chloro-N'-{[3-(6-chloro-3-pyrid-ylmethyl)-2-nitrimino-imidazolidin-1-yl]sulfan-yl}benzo-hydrazide.
2009 Aug 12
Biochemical mechanisms of methoxyfenozide resistance in the cotton leafworm Spodoptera littoralis.
2009 Jul
Feeding cessation effects of chlorantraniliprole, a new anthranilic diamide insecticide, in comparison with several insecticides in distinct chemical classes and mode-of-action groups.
2009 Sep
Cross-resistance between azinphos-methyl and acetamiprid in populations of codling moth, Cydia pomonella (L.) (Lepidoptera: Tortricidae), from Washington State.
2010 Aug
Toxicity and sublethal effects of methoxyfenozide on Spodoptera exigua (Lepidoptera: Noctuidae).
2010 Jun
High levels of miticides and agrochemicals in North American apiaries: implications for honey bee health.
2010 Mar 19
Effects of six selected orchard insecticides on Neoseiulus fallacis (Acari: Phytoseiidae) in the laboratory.
2010 Nov
Exposure to methoxyfenozide-treated surfaces reduces the responsiveness of adult male codling moth (Lepidoptera: Tortricidae) to codlemone and pear ester lures in a wind tunnel.
2010 Oct
[Determination of five diacylhydrazine insecticide residues in welsh onion using high performance liquid chromatography-tandem mass spectrometry].
2010 Sep
Patents
Name Type Language
METHOXYFENOZIDE
ISO   MI  
Common Name English
3-METHOXY-2-METHYLBENZOIC ACID 2-(3,5-DIMETHYLBENZOYL)-2-(1,1-DIMETHYLETHYL)HYDRAZIDE
Common Name English
RH-112485
Code English
RUNNER
Brand Name English
INTREPID
Brand Name English
PRODIGY
Brand Name English
N'-TERT-BUTYL-N'-(3,5-DIMETHYLBENZOYL)-3-METHOXY-2-METHYLBENZOHYDRAZIDE
Systematic Name English
RH-2485
Code English
METHOXYFENOZIDE [MI]
Common Name English
N-TERT-BUTYL-N'-(3-METHOXY-O-TOLUOYL)-3,5-XYLOHYDRAZIDE
Common Name English
METHOXYFENOZIDE [ISO]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 121027
Created by admin on Fri Dec 15 18:11:41 GMT 2023 , Edited by admin on Fri Dec 15 18:11:41 GMT 2023
Code System Code Type Description
HSDB
7936
Created by admin on Fri Dec 15 18:11:41 GMT 2023 , Edited by admin on Fri Dec 15 18:11:41 GMT 2023
PRIMARY
MERCK INDEX
m7336
Created by admin on Fri Dec 15 18:11:41 GMT 2023 , Edited by admin on Fri Dec 15 18:11:41 GMT 2023
PRIMARY Merck Index
FDA UNII
62A22651ZX
Created by admin on Fri Dec 15 18:11:41 GMT 2023 , Edited by admin on Fri Dec 15 18:11:41 GMT 2023
PRIMARY
EPA CompTox
DTXSID3032628
Created by admin on Fri Dec 15 18:11:41 GMT 2023 , Edited by admin on Fri Dec 15 18:11:41 GMT 2023
PRIMARY
CHEBI
38449
Created by admin on Fri Dec 15 18:11:41 GMT 2023 , Edited by admin on Fri Dec 15 18:11:41 GMT 2023
PRIMARY
ALANWOOD
methoxyfenozide
Created by admin on Fri Dec 15 18:11:41 GMT 2023 , Edited by admin on Fri Dec 15 18:11:41 GMT 2023
PRIMARY
CAS
161050-58-4
Created by admin on Fri Dec 15 18:11:41 GMT 2023 , Edited by admin on Fri Dec 15 18:11:41 GMT 2023
PRIMARY
PUBCHEM
105010
Created by admin on Fri Dec 15 18:11:41 GMT 2023 , Edited by admin on Fri Dec 15 18:11:41 GMT 2023
PRIMARY