U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C22H28N2O3
Molecular Weight 368.4693
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHOXYFENOZIDE

SMILES

COC1=C(C)C(=CC=C1)C(=O)NN(C(=O)C2=CC(C)=CC(C)=C2)C(C)(C)C

InChI

InChIKey=QCAWEPFNJXQPAN-UHFFFAOYSA-N
InChI=1S/C22H28N2O3/c1-14-11-15(2)13-17(12-14)21(26)24(22(4,5)6)23-20(25)18-9-8-10-19(27-7)16(18)3/h8-13H,1-7H3,(H,23,25)

HIDE SMILES / InChI

Molecular Formula C22H28N2O3
Molecular Weight 368.4693
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Ecdysone signaling and transcript signature in Drosophila cells resistant against methoxyfenozide.
2010-12
Adaptation of an ecdysone-based genetic switch for transgene expression in soybean seeds.
2010-12
Improvement of ecdysone receptor gene switch for applications in plants: Locusta migratoria retinoid X receptor (LmRXR) mutagenesis and optimization of translation start site.
2010-11
Effects of six selected orchard insecticides on Neoseiulus fallacis (Acari: Phytoseiidae) in the laboratory.
2010-11
Exposure to methoxyfenozide-treated surfaces reduces the responsiveness of adult male codling moth (Lepidoptera: Tortricidae) to codlemone and pear ester lures in a wind tunnel.
2010-10
[Determination of five diacylhydrazine insecticide residues in welsh onion using high performance liquid chromatography-tandem mass spectrometry].
2010-09
Cross-resistance between azinphos-methyl and acetamiprid in populations of codling moth, Cydia pomonella (L.) (Lepidoptera: Tortricidae), from Washington State.
2010-08
Toxicity and sublethal effects of methoxyfenozide on Spodoptera exigua (Lepidoptera: Noctuidae).
2010-06
High levels of miticides and agrochemicals in North American apiaries: implications for honey bee health.
2010-03-19
Feeding cessation effects of chlorantraniliprole, a new anthranilic diamide insecticide, in comparison with several insecticides in distinct chemical classes and mode-of-action groups.
2009-09
N'-Benzoyl-N-tert-butyl-2-chloro-N'-{[3-(6-chloro-3-pyrid-ylmethyl)-2-nitrimino-imidazolidin-1-yl]sulfan-yl}benzo-hydrazide.
2009-08-12
Influence of azadirachtin and methoxyfenozide on life parameters of Spodoptera littoralis (Lepidoptera: Noctuidae).
2009-08
Towards Coleoptera-specific high-throughput screening systems for compounds with ecdysone activity: development of EcR reporter assays using weevil (Anthonomus grandis)-derived cell lines and in silico analysis of ligand binding to A. grandis EcR ligand-binding pocket.
2009-08
Biochemical mechanisms of methoxyfenozide resistance in the cotton leafworm Spodoptera littoralis.
2009-07
Control of grape berry moth (Lepidoptera: Tortricidae) in relation to oviposition phenology.
2009-04
Influence of Lobesia botrana field control on black aspergilli rot and ochratoxin A contamination in grapes.
2009-04
Resistance of Pakistani field populations of spotted bollworm Earias vittella (Lepidoptera: Noctuidae) to pyrethroid, organophosphorus and new chemical insecticides.
2009-04
Integrating chemical and biological control of European corn borer in bell pepper.
2009-02
Effects of larval exposure to sublethal concentrations of methoxyfenozide in Spodoptera frugiperda (J.E. Smith).
2009
Susceptibility of Chrysoperla externa eggs (Neuroptera: Chrisopidae) to conventional and biorational insecticides.
2008-10
Monitoring of beet armyworm resistance to spinosad and methoxyfenozide in Mexico.
2008-10
Effects of classical insect hormones on the expression profiles of a lipase gene from the cotton bollworm (Helicoverpa armigera).
2008-09
Ecdysteroid signaling in ecdysteroid-resistant cell lines from the polyphagous noctuid pest Spodoptera exigua.
2008-09
Assessment of methoxyfenozide exposure on the sexual attractiveness and responsiveness of adult codling moth, Cydia pomonella L., in small orchard blocks.
2008-09
Resistance of codling moth, Cydia pomonella (L.) (Lepidoptera: Tortricidae), larvae in Michigan to insecticides with different modes of action and the impact on field residual activity.
2008-09
Improvement of a monopartite ecdysone receptor gene switch and demonstration of its utility in regulation of transgene expression in plants.
2008-05
The ecological impact of four IGR insecticides in adults of Hyposoter didymator (Hym., Ichneumonidae): pharmacokinetics approach.
2008-04
Selection for resistance to methoxyfenozide and 20-hydroxyecdysone in cells of the beet armyworm, Spodoptera exigua.
2008-01
Efficacy results of insecticides against Cydia pomonella, the codling moth, in Belgium during the last decade (1998-2007).
2008
Molecular cloning and characterization of a C-type lectin from the cotton bollworm, Helicoverpa armigera.
2008
Influence of mixtures of kaolin particle film and synthetic insecticides on mortality of larval obliquebanded leafrollers (Lepidoptera: Tortricidae) from resistant and susceptible populations.
2007-12
Development of a tightly regulated and highly inducible ecdysone receptor gene switch for plants through the use of retinoid X receptor chimeras.
2007-10
Laboratory studies to elucidate the residual toxicity of eight insecticides to Anystis baccarum (Acari: Anystidae).
2007-08
Novel life stage targets against plum curculio, Conotrachelus nenuphar (Herbst), in apple integrated pest management.
2007-08
Applications of EcR gene switch technology in functional genomics.
2007-07
Ovicidal and larvicidal effectiveness of insecticides applied by dipping apples on the small fruit tortrix Grapholita lobarzewskii.
2007-07
Identification and expression profile of a putative basement membrane protein gene in the midgut of Helicoverpa armigera.
2007-06-28
Lethal and sublethal effects of methoxyfenozide and spinosad on Spodoptera littoralis (Lepidoptera: Noctuidae).
2007-06
Effects of ecdysteroid agonist RH-2485 reveal interactions between ecdysteroids and juvenile hormones in the development of Sesamia nonagrioides.
2007-06
QSAR and mode of action studies of insecticidal ecdysone agonists.
2007-03-17
Sublethal exposure to methoxyfenozide-treated surfaces reduces the attractiveness and responsiveness in adult oriental fruit moth (Lepidoptera: Tortricidae).
2007-02
Effect of conventional and biorational insecticides on larvae of Chrysoperla externa.
2007
Bumblebees can be used in combination with juvenile hormone analogues and ecdysone agonists.
2006-08
Tebufenozide resistance selected in Plutella xylostella and its cross-resistance and fitness cost.
2006-08
Cathepsin B-like proteinase is involved in the decomposition of the adult fat body of Helicoverpa armigera.
2006-05
Development of a methoxyfenozide-responsive gene switch for applications in plants.
2006-02
Resistance and cross-resistance in populations of the leafrollers, Choristoneura rosaceana and Pandemis pyrusana , in Washington apples.
2006
Side effects of conventional and non-conventional insecticides on eggs and larvae of Chrysoperla externa (Hagen) (Neuroptera: Chrysopidae) in Argentine.
2006
Efficacy of some plant oils alone and/or combined with different insecticides on the cotton leaf-worm Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae) in Egypt.
2006
Development, oviposition, and mortality of Neoseiulus fallacis (Acari: Phytoseiidae) in response to reduced-risk insecticides.
2005-12
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:07:39 GMT 2025
Edited
by admin
on Mon Mar 31 19:07:39 GMT 2025
Record UNII
62A22651ZX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
INTREPID
Preferred Name English
METHOXYFENOZIDE
ISO   MI  
Common Name English
3-METHOXY-2-METHYLBENZOIC ACID 2-(3,5-DIMETHYLBENZOYL)-2-(1,1-DIMETHYLETHYL)HYDRAZIDE
Common Name English
RH-112485
Code English
RUNNER
Brand Name English
PRODIGY
Brand Name English
N'-TERT-BUTYL-N'-(3,5-DIMETHYLBENZOYL)-3-METHOXY-2-METHYLBENZOHYDRAZIDE
Systematic Name English
RH-2485
Code English
METHOXYFENOZIDE [MI]
Common Name English
N-TERT-BUTYL-N'-(3-METHOXY-O-TOLUOYL)-3,5-XYLOHYDRAZIDE
Common Name English
METHOXYFENOZIDE [ISO]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 121027
Created by admin on Mon Mar 31 19:07:39 GMT 2025 , Edited by admin on Mon Mar 31 19:07:39 GMT 2025
Code System Code Type Description
HSDB
7936
Created by admin on Mon Mar 31 19:07:39 GMT 2025 , Edited by admin on Mon Mar 31 19:07:39 GMT 2025
PRIMARY
MERCK INDEX
m7336
Created by admin on Mon Mar 31 19:07:39 GMT 2025 , Edited by admin on Mon Mar 31 19:07:39 GMT 2025
PRIMARY Merck Index
FDA UNII
62A22651ZX
Created by admin on Mon Mar 31 19:07:39 GMT 2025 , Edited by admin on Mon Mar 31 19:07:39 GMT 2025
PRIMARY
EPA CompTox
DTXSID3032628
Created by admin on Mon Mar 31 19:07:39 GMT 2025 , Edited by admin on Mon Mar 31 19:07:39 GMT 2025
PRIMARY
CHEBI
38449
Created by admin on Mon Mar 31 19:07:39 GMT 2025 , Edited by admin on Mon Mar 31 19:07:39 GMT 2025
PRIMARY
ALANWOOD
methoxyfenozide
Created by admin on Mon Mar 31 19:07:39 GMT 2025 , Edited by admin on Mon Mar 31 19:07:39 GMT 2025
PRIMARY
CAS
161050-58-4
Created by admin on Mon Mar 31 19:07:39 GMT 2025 , Edited by admin on Mon Mar 31 19:07:39 GMT 2025
PRIMARY
PUBCHEM
105010
Created by admin on Mon Mar 31 19:07:39 GMT 2025 , Edited by admin on Mon Mar 31 19:07:39 GMT 2025
PRIMARY