Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C22H28O5 |
| Molecular Weight | 372.4547 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)CC(=O)[C@@]3([H])[C@@]2([H])C[C@H](C)C4=CC(=O)C=C[C@]34C
InChI
InChIKey=SVYCRJXQZUCUND-PQXSVQADSA-N
InChI=1S/C22H28O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,19,23,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,19+,20-,21-,22-/m0/s1
DescriptionCurator's Comment: Note: there is a lot of confusion in the literature about the structure of methylprednisolone vs methylprednisone. Methylprednisolone has OH group at 11th position, whereas methylprednisone has carbonyl (=O) group. In most reported clinical trials where authors reference methylprednisone, methylprednisolone was investigated. See for example https://www.ncbi.nlm.nih.gov/pubmed/12201245
Curator's Comment: Note: there is a lot of confusion in the literature about the structure of methylprednisolone vs methylprednisone. Methylprednisolone has OH group at 11th position, whereas methylprednisone has carbonyl (=O) group. In most reported clinical trials where authors reference methylprednisone, methylprednisolone was investigated. See for example https://www.ncbi.nlm.nih.gov/pubmed/12201245
11-keto methylprednisolone is a metabolite of corticosteroid immunosuppressant methylprednisolone.
Approval Year
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SUB08756MIG
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DB12952
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621XR2W6OP
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63546
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124653
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1435014
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91523-05-6
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PARENT (METABOLITE)
SUBSTANCE RECORD
