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Details

Stereochemistry ACHIRAL
Molecular Formula C3H5N2.C3H4N2.C2H6OS.4Cl.Ru
Molecular Weight 458.18
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0
Stereo Comments [H2im][trans-RuCl4(dmso-S)(Him)]

SHOW SMILES / InChI
Structure of NAMI-A

SMILES

[Cl-].[Cl-].[Cl-].[Cl-].[Ru+3].C[S+](C)[O-].N1C=CN=C1.N2C=C[NH+]=C2

InChI

InChIKey=RJZBTXZRLXLLKO-UHFFFAOYSA-K
InChI=1S/2C3H4N2.C2H6OS.4ClH.Ru/c2*1-2-5-3-4-1;1-4(2)3;;;;;/h2*1-3H,(H,4,5);1-2H3;4*1H;/q;;;;;;;+3/p-3

HIDE SMILES / InChI

Approval Year

Name Type Language
NAMI-A
Common Name English
1H-IMIDAZOLE (OC-6-11)-TETRACHLORO(1H-IMIDAZOLE-.KAPPA.N3)(1,1'-(SULFINYL-.KAPPA.S)BIS(METHANE))RUTHENATE(1-) (1:1)
Systematic Name English
IMIDAZOLIUM-TRANS-TETRACHLORO(DIMETHYLSULFOXIDE)IMIDAZOLERUTHENIUM(III)
Systematic Name English
RUTHENATE(1-), TETRACHLORO(1H-IMIDAZOLE-.KAPPA.N3)(1,1'-(SULFINYL-.KAPPA.S)BIS(METHANE))-, (OC-6-11)-, HYDROGEN, COMPD. WITH 1H-IMIDAZOLE (1:1:1)
Systematic Name English
Code System Code Type Description
FDA UNII
60487Z56XW
Created by admin on Sat Dec 16 11:17:36 GMT 2023 , Edited by admin on Sat Dec 16 11:17:36 GMT 2023
PRIMARY
PUBCHEM
9890346
Created by admin on Sat Dec 16 11:17:36 GMT 2023 , Edited by admin on Sat Dec 16 11:17:36 GMT 2023
PRIMARY
WIKIPEDIA
NAMI-A
Created by admin on Sat Dec 16 11:17:36 GMT 2023 , Edited by admin on Sat Dec 16 11:17:36 GMT 2023
PRIMARY NAMI-A and KP1019 are two ruthenium anticancer agents that have entered clinical trials. NAMI is an acronym for "New Anti-tumour Metastasis Inhibitor", while the -A suffix indicates that this is the first of a potential series. Ruthenium, unlike traditional platinum complexes such as cisplatin, shows greater resistance to hydrolysis and more selective action on tumors.
CAS
201653-76-1
Created by admin on Sat Dec 16 11:17:36 GMT 2023 , Edited by admin on Sat Dec 16 11:17:36 GMT 2023
PRIMARY