NAMI-A

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H5N2.C3H4N2.C2H6OS.4Cl.Ru
Molecular Weight	458.18
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0
Stereo Comments	[H2im][trans-RuCl4(dmso-S)(Him)]

SHOW SMILES / InChI

Structure Search

SMILES

[Cl-].[Cl-].[Cl-].[Cl-].[Ru+3].C[S+](C)[O-].N1C=CN=C1.N2C=C[NH+]=C2

InChI

InChIKey=RJZBTXZRLXLLKO-UHFFFAOYSA-K

InChI=1S/2C3H4N2.C2H6OS.4ClH.Ru/c2*1-2-5-3-4-1;1-4(2)3;;;;;/h2*1-3H,(H,4,5);1-2H3;4*1H;/q;;;;;;;+3/p-3

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Ru
Molecular Weight	101.07
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C3H4N2
Molecular Weight	68.0773
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C2H6OS
Molecular Weight	78.133
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:44:53 GMT 2025` Edited by `admin` on `Mon Mar 31 23:44:53 GMT 2025`
Record UNII	60487Z56XW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1H-IMIDAZOLE (OC-6-11)-TETRACHLORO(1H-IMIDAZOLE-.KAPPA.N3)(1,1'-(SULFINYL-.KAPPA.S)BIS(METHANE))RUTHENATE(1-) (1:1)

Preferred Name

English

NAMI-A

Common Name

English

IMIDAZOLIUM-TRANS-TETRACHLORO(DIMETHYLSULFOXIDE)IMIDAZOLERUTHENIUM(III)

Systematic Name

English

RUTHENATE(1-), TETRACHLORO(1H-IMIDAZOLE-.KAPPA.N3)(1,1'-(SULFINYL-.KAPPA.S)BIS(METHANE))-, (OC-6-11)-, HYDROGEN, COMPD. WITH 1H-IMIDAZOLE (1:1:1)

Systematic Name

English

Code System Code Type Description

FDA UNII

60487Z56XW

Created by admin on Mon Mar 31 23:44:53 GMT 2025 , Edited by admin on Mon Mar 31 23:44:53 GMT 2025

PRIMARY

PUBCHEM

9890346

Created by admin on Mon Mar 31 23:44:53 GMT 2025 , Edited by admin on Mon Mar 31 23:44:53 GMT 2025

PRIMARY

WIKIPEDIA

NAMI-A

Created by admin on Mon Mar 31 23:44:53 GMT 2025 , Edited by admin on Mon Mar 31 23:44:53 GMT 2025

PRIMARY

NAMI-A and KP1019 are two ruthenium anticancer agents that have entered clinical trials. NAMI is an acronym for "New Anti-tumour Metastasis Inhibitor", while the -A suffix indicates that this is the first of a potential series. Ruthenium, unlike traditional platinum complexes such as cisplatin, shows greater resistance to hydrolysis and more selective action on tumors.

CAS

201653-76-1

Created by admin on Mon Mar 31 23:44:53 GMT 2025 , Edited by admin on Mon Mar 31 23:44:53 GMT 2025

PRIMARY

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NAMI-A ANION

ACTIVE MOIETY