Fuchsine (rosaniline hydrochloride) is a magenta dye. Basic fuchsine is a mixture of rosaniline, pararosaniline, new fuchsine and Magenta II. Carbol fuchsin is a mixture of phenol and basic fuchsin, used in bacterial staining procedures. It is commonly used in the staining of mycobacteria as it has an affinity for the mycolic acids found in their cell membranes. The World Health Organization recommendation of 0.3% carbol fuchsin in the ZN method for staining acid-fast bacilli (AFB).
Originator
Approval Year
PubMed
Title | Date | PubMed |
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Identification of mammary carcinogens in rodent bioassays. | 2002 |
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Inhibition of human plasma cholinesterase by malachite green and related triarylmethane dyes: mechanistic implications. | 2005 Aug 15 |
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Assessment of genotoxicity of 14 chemical agents used in dental practice: ability to induce chromosome aberrations in Syrian hamster embryo cells. | 2006 Feb 28 |
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Comparative effects of cationic triarylmethane, phenoxazine and phenothiazine dyes on horse serum butyrylcholinesterase. | 2008 Oct 15 |
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Inhibition of electric eel acetylcholinesterase by triarylmethane dyes. | 2008 Sep 25 |
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Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. | 2009 Mar 24 |
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FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1. | 2013 Sep 5 |
Sample Use Guides
Apply a small amount of solution contatining basic fuchsin on the area one to three times daily.
Route of Administration:
Topical
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3989507
The effect of basic fuchsin on the growth of
mycoplasmas was tested at concentrations from 0.6 mg/L to 0.3 g/L.
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C45178
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C461
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SUB15146MIG
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C44332
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CHEMBL220998
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Basic fuchsin
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1535513
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All of the following components must be present:
SUBSTANCE RECORD