BASIC VIOLET 14

US Previously Marketed

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H19N3.ClH
Molecular Weight	337.846
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC1=C(N)C=CC(=C1)C(C2=CC=C(N)C=C2)=C3C=CC(=N)C=C3

InChI

InChIKey=NIKFYOSELWJIOF-SVFFXJIWSA-N

InChI=1S/C20H19N3.ClH/c1-13-12-16(6-11-19(13)23)20(14-2-7-17(21)8-3-14)15-4-9-18(22)10-5-15;/h2-12,21H,22-23H2,1H3;1H/b20-14-,21-17?;

HIDE SMILES / InChI

Molecular Formula	C20H19N3
Molecular Weight	301.385
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://monographs.iarc.fr/ENG/Monographs/vol99/mono99-12.pdf | https://www.ncbi.nlm.nih.gov/pubmed/12609582https://www.ncbi.nlm.nih.gov/pubmed/12149374

Fuchsine (rosaniline hydrochloride) is a magenta dye. Basic fuchsine is a mixture of rosaniline, pararosaniline, new fuchsine and Magenta II. Carbol fuchsin is a mixture of phenol and basic fuchsin, used in bacterial staining procedures. It is commonly used in the staining of mycobacteria as it has an affinity for the mycolic acids found in their cell membranes. The World Health Organization recommendation of 0.3% carbol fuchsin in the ZN method for staining acid-fast bacilli (AFB).

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Skin infections 59 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12609582	Curative		Approved 8429	CASTELLANI PAINT Approved Use First aid antiseptic to help protect against skin infection in minor cuts, scrapes or burns
Unknown 2578

PubMed

Title	Date	PubMed
Identification of mammary carcinogens in rodent bioassays.	2002	11921183
Inhibition of human plasma cholinesterase by malachite green and related triarylmethane dyes: mechanistic implications.	2005 Aug 15	16036213
Assessment of genotoxicity of 14 chemical agents used in dental practice: ability to induce chromosome aberrations in Syrian hamster embryo cells.	2006 Feb 28	16406784
Comparative effects of cationic triarylmethane, phenoxazine and phenothiazine dyes on horse serum butyrylcholinesterase.	2008 Oct 15	18656440
Inhibition of electric eel acetylcholinesterase by triarylmethane dyes.	2008 Sep 25	18571634
Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening.	2009 Mar 24	19255438
FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.	2013 Sep 5	23769903

Patents

Sample Use Guides

In Vivo Use Guide

Apply a small amount of solution contatining basic fuchsin on the area one to three times daily.

Route of Administration: Topical

In Vitro Use Guide

The effect of basic fuchsin on the growth of mycoplasmas was tested at concentrations from 0.6 mg/L to 0.3 g/L.

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:39:19 UTC 2023` Edited by `admin` on `Fri Dec 15 15:39:19 UTC 2023`
Record UNII	8UUC89LHB2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BASIC VIOLET 14

Official Name

English

FUCHSINE

Common Name

English

FUCHSIN

Common Name

English

4-((4-AMINOPHENYL)(4-IMINO-2,5-CYCLOHEXADIEN-1-YLIDENE)METHYL)-2- METHYLBENZENAMINE MONOHYDROCHLORIDE

Systematic Name

English

CI 42510

Official Name

English

CI 42510 [INCI]

Common Name

English

NSC-10466

Code

English

MAGENTA I

Common Name

English

NSC-93739

Code

English

BASIC VIOLET 14 [INCI]

Common Name

English

MAGENTA I [MI]

Common Name

English

LOWACRYL VIOLET 14

Common Name

English

BENZENEAMINE, 4-((4-AMINOPHENYL)(4-IMINO-2,5-CYCLOHEXADIEN-1-YLIDENE)METHYL)-2-METHYL-, MONOHYDROCHLORIDE

Common Name

English

C.I. BASIC VIOLET 14

Common Name

English

ROSANILINE HCL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C461