U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C5H6N2O2
Molecular Weight 126.1133
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 6-METHYLURACIL

SMILES

CC1=CC(=O)NC(=O)N1

InChI

InChIKey=SHVCSCWHWMSGTE-UHFFFAOYSA-N
InChI=1S/C5H6N2O2/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
1,3-Bis(4-meth-oxy-benz-yl)-6-methyl-pyrimidine-2,4(1H,3H)-dione.
2010-06-30
An evaluation of the chick cardiomyocyte micromass system for identification of teratogens in a blind trial.
2009-12
Mechanisms of cardiac muscle insensitivity to a novel acetylcholinesterase inhibitor C-547.
2009-02
Different sensitivity of miniature endplate currents in rat external and internal intercostal muscles to the acetylcholinesterase inhibitor C-547 as compared with diaphragm and extensor digitorum longus.
2009
Compounds with the dioxopyrimidine cycle inhibit cholinesterases from different groups of animals.
2008-09-25
Tetrakis- and tris(1-Methyluracil) complexes of Pt(II): formation and properties of a carbon-bonded nucleobase species as well as of heternonuclear derivatives.
2007-12-24
[Studying the nootropic effects of betamecil].
2007-12-15
The design and synthesis of N-1-alkylated-5-aminoarylalkylsubstituted-6-methyluracils as potential non-nucleoside HIV-1 RT inhibitors.
2007-12-01
Effect of a tetraalkylammonium derivative of 6-methyluracil from a new class of acetylcholinesterase inhibitors on the endplate potential amplitude in muscles of different function types under high-frequency nerve stimulation.
2007-10-13
Selective oxidation of key functional groups in cyanotoxins during drinking water ozonation.
2007-06-15
[Realization of optic activatory mechanism in laser-medication impact].
2006-06-07
Different sensitivity of miniature endplate currents of the rat extensor digitorum longus, soleus and diaphragm muscles to a novel acetylcholinesterase inhibitor C-547.
2006
Reaction of substituted pyrimidines with photochemically generated t-BuO* radicals.
2005-12
Effect of tetraalkylammonium derivatives of 6-methyluracil on the endplate potentials of muscles of different functional types.
2005-02-19
Electron impact mass spectral study of 1,2-di-o-(m- and p-)nitro-(bromo-)benzyl-2-thio-6-methyluracils and 1,2-di-o-(m- and p-)nitro-(bromo-)benzyl-2-thio-5-bromo-6-methyluracils.
2005
Biological activity of bacterial lectins and their molecular complexes with heterocyclic bis-adducts.
2004-01-16
Antiparasitic activity of highly conjugated pyrimidine-2,4-dione derivatives.
2003-12
Pyrrolidino-DNA.
2003-10-21
[Surgical infected wound treatment in patients with severe gastrointestinal ulcer hemorrhage].
2003-01-29
[Current methods for local drug therapy of infected wounds].
2003
[Photophoresis of methyluracil ointment in the complex treatment of temporomandibular pain syndrome].
2002-09-12
The acidity of uracil and uracil analogs in the gas phase: four surprisingly acidic sites and biological implications.
2002-08
Genotoxicity study of a new tetraalkylammonium derivative of 6-methyluracil (agent No. 547).
2002-03
[Morphological aspects of dermatotrophic action of methyluracil applied epicutaneously].
2002
[Studies of biological activity of mineral oil dialkyl disulfide (an experimental study)].
2002
Tetraalkylammonium derivatives of 6-methyluracil, a new class of cholinesterase inhibitors: characteristics of interaction with cholinesterases from different groups of animals.
2001-11-20
Effect of tetraalkylammonium derivative of 6-methyluracil on amplitude and temporal parameters of miniature endplate potentials in frog neuromuscular junction.
2001-05
Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii.
1994-08-17
Patents
Name Type Language
6-METHYLURACIL
HSDB   MI  
Systematic Name English
METHYLURACIL
WHO-DD  
Preferred Name English
4-METHYLURACIL
Common Name English
Methyluracil [WHO-DD]
Common Name English
6-METHYLURACIL [MI]
Common Name English
NSC-9456
Code English
6-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE
Systematic Name English
6-METHYLURACIL [HSDB]
Common Name English
METHYLURACIL, 4-
Common Name English
Code System Code Type Description
PUBCHEM
12283
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY
ECHA (EC/EINECS)
210-949-4
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY
FDA UNII
5O052W0G6I
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY
MERCK INDEX
m7479
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY Merck Index
EVMPD
SUB71917
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY
SMS_ID
100000089069
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY
NSC
9456
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY
CAS
626-48-2
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY
EVMPD
SUB22952
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY
HSDB
5508
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY
EPA CompTox
DTXSID8052308
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY
MESH
C008378
Created by admin on Mon Mar 31 18:44:35 GMT 2025 , Edited by admin on Mon Mar 31 18:44:35 GMT 2025
PRIMARY