6-METHYLURACIL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H6N2O2
Molecular Weight	126.1133
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC(=O)NC(=O)N1

InChI

InChIKey=SHVCSCWHWMSGTE-UHFFFAOYSA-N

InChI=1S/C5H6N2O2/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)

HIDE SMILES / InChI

Molecular Formula	C5H6N2O2
Molecular Weight	126.1133
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
nucleic acid metabolic process 2 Target ID: GO:0090304 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5641146	Modulator 846

PubMed

Title	Date	PubMed
1,3-Bis(4-meth-oxy-benz-yl)-6-methyl-pyrimidine-2,4(1H,3H)-dione.	2010-06-30	21588055
An evaluation of the chick cardiomyocyte micromass system for identification of teratogens in a blind trial.	2009-12	19646523
Mechanisms of cardiac muscle insensitivity to a novel acetylcholinesterase inhibitor C-547.	2009-02	19188831
Different sensitivity of miniature endplate currents in rat external and internal intercostal muscles to the acetylcholinesterase inhibitor C-547 as compared with diaphragm and extensor digitorum longus.	2009	19331513
Compounds with the dioxopyrimidine cycle inhibit cholinesterases from different groups of animals.	2008-09-25	18585370
Tetrakis- and tris(1-Methyluracil) complexes of Pt(II): formation and properties of a carbon-bonded nucleobase species as well as of heternonuclear derivatives.	2007-12-24	18047329
[Studying the nootropic effects of betamecil].	2007-12-15	18078033
The design and synthesis of N-1-alkylated-5-aminoarylalkylsubstituted-6-methyluracils as potential non-nucleoside HIV-1 RT inhibitors.	2007-12-01	17870545
Effect of a tetraalkylammonium derivative of 6-methyluracil from a new class of acetylcholinesterase inhibitors on the endplate potential amplitude in muscles of different function types under high-frequency nerve stimulation.	2007-10-13	17929660
Selective oxidation of key functional groups in cyanotoxins during drinking water ozonation.	2007-06-15	17626442
[Realization of optic activatory mechanism in laser-medication impact].	2006-06-07	16752823
Different sensitivity of miniature endplate currents of the rat extensor digitorum longus, soleus and diaphragm muscles to a novel acetylcholinesterase inhibitor C-547.	2006	16792471
Reaction of substituted pyrimidines with photochemically generated t-BuO* radicals.	2005-12	16955740
Effect of tetraalkylammonium derivatives of 6-methyluracil on the endplate potentials of muscles of different functional types.	2005-02-19	15717607
Electron impact mass spectral study of 1,2-di-o-(m- and p-)nitro-(bromo-)benzyl-2-thio-6-methyluracils and 1,2-di-o-(m- and p-)nitro-(bromo-)benzyl-2-thio-5-bromo-6-methyluracils.	2005	15678523
Biological activity of bacterial lectins and their molecular complexes with heterocyclic bis-adducts.	2004-01-16	14723158
Antiparasitic activity of highly conjugated pyrimidine-2,4-dione derivatives.	2003-12	14630237
Pyrrolidino-DNA.	2003-10-21	14565376
[Surgical infected wound treatment in patients with severe gastrointestinal ulcer hemorrhage].	2003-01-29	12549260
[Current methods for local drug therapy of infected wounds].	2003	12645211
[Photophoresis of methyluracil ointment in the complex treatment of temporomandibular pain syndrome].	2002-09-12	12221836
The acidity of uracil and uracil analogs in the gas phase: four surprisingly acidic sites and biological implications.	2002-08	12216739
Genotoxicity study of a new tetraalkylammonium derivative of 6-methyluracil (agent No. 547).	2002-03	11914783
[Morphological aspects of dermatotrophic action of methyluracil applied epicutaneously].	2002	12530313
[Studies of biological activity of mineral oil dialkyl disulfide (an experimental study)].	2002	12520911
Tetraalkylammonium derivatives of 6-methyluracil, a new class of cholinesterase inhibitors: characteristics of interaction with cholinesterases from different groups of animals.	2001-11-20	11712130
Effect of tetraalkylammonium derivative of 6-methyluracil on amplitude and temporal parameters of miniature endplate potentials in frog neuromuscular junction.	2001-05	11550049
Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii.	1994-08-17	8080452

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:44:35 GMT 2025` Edited by `admin` on `Mon Mar 31 18:44:35 GMT 2025`
Record UNII	5O052W0G6I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

6-METHYLURACIL

Systematic Name

English

METHYLURACIL

Preferred Name

English

4-METHYLURACIL

Common Name

English

Methyluracil [WHO-DD]

Common Name

English

6-METHYLURACIL [MI]

Common Name

English

NSC-9456

Code

English

6-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE

Systematic Name

English

6-METHYLURACIL [HSDB]

Common Name

English

METHYLURACIL, 4-

Common Name

English

Code System Code Type Description

PUBCHEM

12283