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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H24N4O
Molecular Weight 372.4629
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ABT-288

SMILES

CN1C[C@H]2CCN([C@H]2C1)C3=CC=C(C=C3)C4=CC=C(C=C4)N5N=CC=CC5=O

InChI

InChIKey=GNIRITULTPTAQW-KNQAVFIVSA-N
InChI=1S/C23H24N4O/c1-25-15-19-12-14-26(22(19)16-25)20-8-4-17(5-9-20)18-6-10-21(11-7-18)27-23(28)3-2-13-24-27/h2-11,13,19,22H,12,14-16H2,1H3/t19-,22+/m1/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Safety, tolerability and pharmacokinetics of the histamine H3 receptor antagonist, ABT-288, in healthy young adults and elderly volunteers.
2013-05
Pharmacological properties and procognitive effects of ABT-288, a potent and selective histamine H3 receptor antagonist.
2012-10
Patents
Name Type Language
ABT-288
Common Name English
2-(4'-((3AR,6AR)-HEXAHYDRO-5-METHYLPYRROLO(3,4-B)PYRROL-1(2H)-YL)(1,1'-BIPHENYL)-4-YL)-3(2H)-PYRIDAZINONE
Preferred Name English
3(2H)-PYRIDAZINONE, 2-(4'-((3AR,6AR)-HEXAHYDRO-5-METHYLPYRROLO(3,4-B)PYRROL-1(2H)-YL)(1,1'-BIPHENYL)-4-YL)-
Systematic Name English
Code System Code Type Description
CAS
948845-91-8
Created by admin on Mon Mar 31 21:09:32 GMT 2025 , Edited by admin on Mon Mar 31 21:09:32 GMT 2025
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SMS_ID
100000175498
Created by admin on Mon Mar 31 21:09:32 GMT 2025 , Edited by admin on Mon Mar 31 21:09:32 GMT 2025
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FDA UNII
5MEI1M3NHH
Created by admin on Mon Mar 31 21:09:32 GMT 2025 , Edited by admin on Mon Mar 31 21:09:32 GMT 2025
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PUBCHEM
24743471
Created by admin on Mon Mar 31 21:09:32 GMT 2025 , Edited by admin on Mon Mar 31 21:09:32 GMT 2025
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DRUG BANK
DB15192
Created by admin on Mon Mar 31 21:09:32 GMT 2025 , Edited by admin on Mon Mar 31 21:09:32 GMT 2025
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