U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C23H24N4O.C4H6O6
Molecular Weight 522.5497
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ABT-288 TARTRATE

SMILES

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CN1C[C@H]2CCN([C@H]2C1)C3=CC=C(C=C3)C4=CC=C(C=C4)N5N=CC=CC5=O

InChI

InChIKey=OBDKKKBDRYYDNK-SJZYVRFBSA-N
InChI=1S/C23H24N4O.C4H6O6/c1-25-15-19-12-14-26(22(19)16-25)20-8-4-17(5-9-20)18-6-10-21(11-7-18)27-23(28)3-2-13-24-27;5-1(3(7)8)2(6)4(9)10/h2-11,13,19,22H,12,14-16H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t19-,22+;1-,2-/m11/s1

HIDE SMILES / InChI

Molecular Formula C4H6O6
Molecular Weight 150.0868
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula C23H24N4O
Molecular Weight 372.4629
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Safety, tolerability and pharmacokinetics of the histamine H3 receptor antagonist, ABT-288, in healthy young adults and elderly volunteers.
2013-05
Pharmacological properties and procognitive effects of ABT-288, a potent and selective histamine H3 receptor antagonist.
2012-10
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:11:22 GMT 2025
Edited
by admin
on Mon Mar 31 21:11:22 GMT 2025
Record UNII
OA5X2NXG68
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ABT-288 TARTRATE
Preferred Name English
Code System Code Type Description
FDA UNII
OA5X2NXG68
Created by admin on Mon Mar 31 21:11:22 GMT 2025 , Edited by admin on Mon Mar 31 21:11:22 GMT 2025
PRIMARY
PUBCHEM
68494919
Created by admin on Mon Mar 31 21:11:22 GMT 2025 , Edited by admin on Mon Mar 31 21:11:22 GMT 2025
PRIMARY
CAS
948846-43-3
Created by admin on Mon Mar 31 21:11:22 GMT 2025 , Edited by admin on Mon Mar 31 21:11:22 GMT 2025
NON-SPECIFIC STOICHIOMETRY
ChEMBL
CHEMBL3545029
Created by admin on Mon Mar 31 21:11:22 GMT 2025 , Edited by admin on Mon Mar 31 21:11:22 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY