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Details

Stereochemistry ACHIRAL
Molecular Formula C2H7N3
Molecular Weight 73.0971
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHYLGUANIDINE

SMILES

CNC(N)=N

InChI

InChIKey=CHJJGSNFBQVOTG-UHFFFAOYSA-N
InChI=1S/C2H7N3/c1-5-2(3)4/h1H3,(H4,3,4,5)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Electrostatics of deformable lipid membranes.
2010-06-16
Curcumin attenuates airway hyperreactivity induced by ischemia-reperfusion of the pancreas in rats.
2010-04
Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase.
2010-03-05
Methylguanidinium borohydride: an ionic-liquid-based hydrogen-storage material.
2010-03-01
Treatment with NZ-419 (5-Hydroxy-1-methylimidazoline-2,4-dione), a novel intrinsic antioxidant, against the progression of chronic kidney disease at stages 3 and 4 in rats.
2010
Effects of the antioxidants lycium barbarum and ascorbic acid on reperfusion liver injury in rats.
2009-12
Effect of N-[Imino(4-morpholyl)methyl]guanidine on the oxidative status in rats with toxic hepatitis.
2009-10
Guanidino compounds as uremic (neuro)toxins.
2009-08-28
Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics.
2009-08-13
The generation of lucigenin chemiluminescence from the reaction of guanidino compounds with phenylglyoxal under alkaline conditions and its application.
2009-07
First indications demonstrating the preventive effects of NZ-419, a novel intrinsic antioxidant, on the initiation and/or progression of chronic renal failure in rats.
2009-07
Impact of increasing haemodialysis frequency versus haemodialysis duration on removal of urea and guanidino compounds: a kinetic analysis.
2009-07
Enhancement effects of hypercapnia on the acute lung injury caused by acid aspiration.
2009-06-30
Production of uremic toxin methylguanidine from creatinine via creatol on activated carbon.
2009-05-01
Transport of guanidine compounds by human organic cation transporters, hOCT1 and hOCT2.
2009-04-15
Protonate3D: assignment of ionization states and hydrogen coordinates to macromolecular structures.
2009-04
Inhibitory effect of antioxidants on hydroxyl radical generation from methylguanidine: an ESR study.
2009-04
Partially hydrolyzed guar gum supplement reduces high-fat diet increased blood lipids and oxidative stress and ameliorates FeCl3-induced acute arterial injury in hamsters.
2009-02-02
The protective effects of green tea extract against L-arginine toxicity to cultured human mesangial cells.
2009-01
Matrix-assisted laser desorption/ionization mass spectrometric analysis of polysulfated-derived oligosaccharides using pyrenemethylguanidine.
2009-01
Potentials and limitations of microorganisms as renal failure biotherapeutics.
2009
Biological effects of electrolyzed water in hemodialysis.
2009
Inhibitory effect of fermented papaya preparation on hydroxyl radical generation from methylguanidine.
2008-11
A new protein architecture for processing alkylation damaged DNA: the crystal structure of DNA glycosylase AlkD.
2008-08-01
Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery.
2008-07-02
The involvement of nitric oxide, nitric oxide synthase, neutrophil elastase, myeloperoxidase and proinflammatory cytokines in the acute lung injury caused by phorbol myristate acetate.
2008-07
Experimental evidence for an inverse hydrogen migration in arginine radicals.
2008-06-18
Accumulation of methylguanidine and changes in guanidino compound levels in plasma, urine, and kidneys of furosemide-treated rats.
2008-06
Oxidative and nitrosative mediators in hepatic injury caused by whole body hyperthermia in rats.
2008-04-30
Protective effects of propofol on acute lung injury induced by oleic acid in conscious rats.
2008-04
The detrimental role of inducible nitric oxide synthase in the pulmonary edema caused by hypercalcemia in conscious rats and isolated lungs.
2008-03
Nitric oxide mediates acute lung injury caused by fat embolism in isolated rat's lungs.
2008-02
N-acetylcysteine attenuates acute lung injury induced by fat embolism.
2008-02
Niacinamide abrogates the organ dysfunction and acute lung injury caused by endotoxin.
2007-09
Clinical and pathological features of fat embolism with acute respiratory distress syndrome.
2007-09
Complex compartmental behavior of small water-soluble uremic retention solutes: evaluation by direct measurements in plasma and erythrocytes.
2007-08
Nicotinamide abrogates acute lung injury caused by ischaemia/reperfusion.
2007-08
Pathophysiological mechanism of lung injury in patients with leptospirosis.
2007-06
Ischemia/reperfusion of the liver induces heart injury in rats.
2007-05
Endotoxin-induced acute lung injury and organ dysfunction are attenuated by pentobarbital anaesthesia.
2007-04-19
Effects of acute renal failure and ganciclovir on the pharmacodynamics of levofloxacin-induced seizures in rats.
2007-04
Inhibition of inducible nitric oxide synthase attenuates acute endotoxin-induced lung injury in rats.
2007-04
Molecular dynamics and density functional studies of substrate binding and catalysis of arginine deiminase.
2007-03-29
Exercise training attenuates septic responses in conscious rats.
2007-03
Endotoxin-induced acute lung injury is enhanced in rats with spontaneous hypertension.
2007-01-05
Urinary excretion of creatol, an in vivo biomarker of hydroxyl radical, in patients with chronic renal failure.
2007
N-acetylcysteine attenuates the acute lung injury caused by phorbol myristate acetate in isolated rat lungs.
2007
Novel acetylcholinesterase target site for malaria mosquito control.
2006-12-20
Unique and common metabolites of thiamethoxam, clothianidin, and dinotefuran in mice.
2006-11
Reperfusion liver injury induces down-regulation of eNOS and up-regulation of iNOS in lung tissues.
2006-09
Patents

Patents

Name Type Language
METHYLGUANIDINE
MI  
Systematic Name English
METHYLGUANIDINE [MI]
Preferred Name English
N-METHYLGUANIDINE
Systematic Name English
Code System Code Type Description
CAS
471-29-4
Created by admin on Mon Mar 31 18:44:33 GMT 2025 , Edited by admin on Mon Mar 31 18:44:33 GMT 2025
PRIMARY
CHEBI
16628
Created by admin on Mon Mar 31 18:44:33 GMT 2025 , Edited by admin on Mon Mar 31 18:44:33 GMT 2025
PRIMARY
MERCK INDEX
m7425
Created by admin on Mon Mar 31 18:44:33 GMT 2025 , Edited by admin on Mon Mar 31 18:44:33 GMT 2025
PRIMARY Merck Index
PUBCHEM
10111
Created by admin on Mon Mar 31 18:44:33 GMT 2025 , Edited by admin on Mon Mar 31 18:44:33 GMT 2025
PRIMARY
FDA UNII
5L0H5Q9VAG
Created by admin on Mon Mar 31 18:44:33 GMT 2025 , Edited by admin on Mon Mar 31 18:44:33 GMT 2025
PRIMARY
ECHA (EC/EINECS)
207-438-3
Created by admin on Mon Mar 31 18:44:33 GMT 2025 , Edited by admin on Mon Mar 31 18:44:33 GMT 2025
PRIMARY
EPA CompTox
DTXSID4020872
Created by admin on Mon Mar 31 18:44:33 GMT 2025 , Edited by admin on Mon Mar 31 18:44:33 GMT 2025
PRIMARY
CHEBI
57840
Created by admin on Mon Mar 31 18:44:33 GMT 2025 , Edited by admin on Mon Mar 31 18:44:33 GMT 2025
PRIMARY
MESH
D008760
Created by admin on Mon Mar 31 18:44:33 GMT 2025 , Edited by admin on Mon Mar 31 18:44:33 GMT 2025
PRIMARY