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Details

Stereochemistry ACHIRAL
Molecular Formula C2H7N3
Molecular Weight 73.0971
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHYLGUANIDINE

SMILES

CNC(N)=N

InChI

InChIKey=CHJJGSNFBQVOTG-UHFFFAOYSA-N
InChI=1S/C2H7N3/c1-5-2(3)4/h1H3,(H4,3,4,5)

HIDE SMILES / InChI

Molecular Formula C2H7N3
Molecular Weight 73.0971
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Novel acetylcholinesterase target site for malaria mosquito control.
2006 Dec 20
Unique and common metabolites of thiamethoxam, clothianidin, and dinotefuran in mice.
2006 Nov
Reperfusion liver injury induces down-regulation of eNOS and up-regulation of iNOS in lung tissues.
2006 Sep
Urinary excretion of creatol, an in vivo biomarker of hydroxyl radical, in patients with chronic renal failure.
2007
N-acetylcysteine attenuates the acute lung injury caused by phorbol myristate acetate in isolated rat lungs.
2007
Effects of acute renal failure and ganciclovir on the pharmacodynamics of levofloxacin-induced seizures in rats.
2007 Apr
Inhibition of inducible nitric oxide synthase attenuates acute endotoxin-induced lung injury in rats.
2007 Apr
Complex compartmental behavior of small water-soluble uremic retention solutes: evaluation by direct measurements in plasma and erythrocytes.
2007 Aug
Nicotinamide abrogates acute lung injury caused by ischaemia/reperfusion.
2007 Aug
Endotoxin-induced acute lung injury is enhanced in rats with spontaneous hypertension.
2007 Jan-Feb
Pathophysiological mechanism of lung injury in patients with leptospirosis.
2007 Jun
Exercise training attenuates septic responses in conscious rats.
2007 Mar
Molecular dynamics and density functional studies of substrate binding and catalysis of arginine deiminase.
2007 Mar 29
Ischemia/reperfusion of the liver induces heart injury in rats.
2007 May
Endotoxin-induced acute lung injury and organ dysfunction are attenuated by pentobarbital anaesthesia.
2007 May-Jun
Niacinamide abrogates the organ dysfunction and acute lung injury caused by endotoxin.
2007 Sep
Clinical and pathological features of fat embolism with acute respiratory distress syndrome.
2007 Sep
Protective effects of propofol on acute lung injury induced by oleic acid in conscious rats.
2008 Apr
Oxidative and nitrosative mediators in hepatic injury caused by whole body hyperthermia in rats.
2008 Apr 30
A new protein architecture for processing alkylation damaged DNA: the crystal structure of DNA glycosylase AlkD.
2008 Aug 1
Nitric oxide mediates acute lung injury caused by fat embolism in isolated rat's lungs.
2008 Feb
N-acetylcysteine attenuates acute lung injury induced by fat embolism.
2008 Feb
The involvement of nitric oxide, nitric oxide synthase, neutrophil elastase, myeloperoxidase and proinflammatory cytokines in the acute lung injury caused by phorbol myristate acetate.
2008 Jul
Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery.
2008 Jul 2
Accumulation of methylguanidine and changes in guanidino compound levels in plasma, urine, and kidneys of furosemide-treated rats.
2008 Jun
Experimental evidence for an inverse hydrogen migration in arginine radicals.
2008 Jun 18
The detrimental role of inducible nitric oxide synthase in the pulmonary edema caused by hypercalcemia in conscious rats and isolated lungs.
2008 Mar
Inhibitory effect of fermented papaya preparation on hydroxyl radical generation from methylguanidine.
2008 Nov
Potentials and limitations of microorganisms as renal failure biotherapeutics.
2009
Biological effects of electrolyzed water in hemodialysis.
2009
Protonate3D: assignment of ionization states and hydrogen coordinates to macromolecular structures.
2009 Apr
Inhibitory effect of antioxidants on hydroxyl radical generation from methylguanidine: an ESR study.
2009 Apr
Transport of guanidine compounds by human organic cation transporters, hOCT1 and hOCT2.
2009 Apr 15
Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics.
2009 Aug 13
Effects of the antioxidants lycium barbarum and ascorbic acid on reperfusion liver injury in rats.
2009 Dec
Partially hydrolyzed guar gum supplement reduces high-fat diet increased blood lipids and oxidative stress and ameliorates FeCl3-induced acute arterial injury in hamsters.
2009 Feb 2
The protective effects of green tea extract against L-arginine toxicity to cultured human mesangial cells.
2009 Jan
Matrix-assisted laser desorption/ionization mass spectrometric analysis of polysulfated-derived oligosaccharides using pyrenemethylguanidine.
2009 Jan
The generation of lucigenin chemiluminescence from the reaction of guanidino compounds with phenylglyoxal under alkaline conditions and its application.
2009 Jul
First indications demonstrating the preventive effects of NZ-419, a novel intrinsic antioxidant, on the initiation and/or progression of chronic renal failure in rats.
2009 Jul
Impact of increasing haemodialysis frequency versus haemodialysis duration on removal of urea and guanidino compounds: a kinetic analysis.
2009 Jul
Guanidino compounds as uremic (neuro)toxins.
2009 Jul-Aug
Enhancement effects of hypercapnia on the acute lung injury caused by acid aspiration.
2009 Jun 30
Production of uremic toxin methylguanidine from creatinine via creatol on activated carbon.
2009 May 1
Effect of N-[Imino(4-morpholyl)methyl]guanidine on the oxidative status in rats with toxic hepatitis.
2009 Oct
Treatment with NZ-419 (5-Hydroxy-1-methylimidazoline-2,4-dione), a novel intrinsic antioxidant, against the progression of chronic kidney disease at stages 3 and 4 in rats.
2010
Curcumin attenuates airway hyperreactivity induced by ischemia-reperfusion of the pancreas in rats.
2010 Apr
Electrostatics of deformable lipid membranes.
2010 Jun 16
Methylguanidinium borohydride: an ionic-liquid-based hydrogen-storage material.
2010 Mar 1
Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase.
2010 Mar 5
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 17:19:22 GMT 2023
Edited
by admin
on Fri Dec 15 17:19:22 GMT 2023
Record UNII
5L0H5Q9VAG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
METHYLGUANIDINE
MI  
Systematic Name English
N-METHYLGUANIDINE
Systematic Name English
METHYLGUANIDINE [MI]
Common Name English
Code System Code Type Description
CAS
471-29-4
Created by admin on Fri Dec 15 17:19:22 GMT 2023 , Edited by admin on Fri Dec 15 17:19:22 GMT 2023
PRIMARY
CHEBI
16628
Created by admin on Fri Dec 15 17:19:22 GMT 2023 , Edited by admin on Fri Dec 15 17:19:22 GMT 2023
PRIMARY
MERCK INDEX
m7425
Created by admin on Fri Dec 15 17:19:22 GMT 2023 , Edited by admin on Fri Dec 15 17:19:22 GMT 2023
PRIMARY Merck Index
PUBCHEM
10111
Created by admin on Fri Dec 15 17:19:22 GMT 2023 , Edited by admin on Fri Dec 15 17:19:22 GMT 2023
PRIMARY
FDA UNII
5L0H5Q9VAG
Created by admin on Fri Dec 15 17:19:22 GMT 2023 , Edited by admin on Fri Dec 15 17:19:22 GMT 2023
PRIMARY
ECHA (EC/EINECS)
207-438-3
Created by admin on Fri Dec 15 17:19:22 GMT 2023 , Edited by admin on Fri Dec 15 17:19:22 GMT 2023
PRIMARY
EPA CompTox
DTXSID4020872
Created by admin on Fri Dec 15 17:19:22 GMT 2023 , Edited by admin on Fri Dec 15 17:19:22 GMT 2023
PRIMARY
CHEBI
57840
Created by admin on Fri Dec 15 17:19:22 GMT 2023 , Edited by admin on Fri Dec 15 17:19:22 GMT 2023
PRIMARY
MESH
D008760
Created by admin on Fri Dec 15 17:19:22 GMT 2023 , Edited by admin on Fri Dec 15 17:19:22 GMT 2023
PRIMARY