Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C20H22O7 |
| Molecular Weight | 374.3845 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C(O)C=CC(C[C@@H]2COC(=O)[C@@]2(O)CC3=CC(OC)=C(O)C=C3)=C1
InChI
InChIKey=ZITBJWXLODLDRH-JLTOFOAXSA-N
InChI=1S/C20H22O7/c1-25-17-8-12(3-5-15(17)21)7-14-11-27-19(23)20(14,24)10-13-4-6-16(22)18(9-13)26-2/h3-6,8-9,14,21-22,24H,7,10-11H2,1-2H3/t14-,20-/m1/s1
Wikstromol is the enantiomer of nortrachelogenin, isolated from Trachelospermum asiaticum var. intermedium and Pinus palustris. Wikstromol exhibited acetylcholinesterase (AChE) inhibitory. It has been found to be active against P-388 lymphocytic leukemia growth implanted in mice. The reason for this is at present unclear, although it is possible that wikstromol is either metabolized to an active antileukemic agent by the host or else serves as a biological response modifier.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| (+)-Nortrachelogenin, A New Pharmacologically Active Lignan From Wikstroemia indica. | 1979 Mar |
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| (+)Nortrachelogenin, a new pharmacologically active lignan from Wikstroemia indica. | 1979 Mar-Apr |
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| (+)-Nortrachelogenin, a new pharmacologically active lignan from Wikstroemia indica. | 1979 Mar-Apr |
|
| Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. | 2000 Aug |
Patents
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5HG1T9G09U
Created by
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61521-74-2
Created by
admin on Sat Dec 16 08:38:28 GMT 2023 , Edited by admin on Sat Dec 16 08:38:28 GMT 2023
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479756
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admin on Sat Dec 16 08:38:28 GMT 2023 , Edited by admin on Sat Dec 16 08:38:28 GMT 2023
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DTXSID70977093
Created by
admin on Sat Dec 16 08:38:28 GMT 2023 , Edited by admin on Sat Dec 16 08:38:28 GMT 2023
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PRIMARY |
SUBSTANCE RECORD
