EPICILLIN SODIUM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C16H20N3O4S.Na
Molecular Weight	373.402
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)C3=CCC=CC3)C(=O)N2[C@H]1C([O-])=O

InChI

InChIKey=WQSDWKIPNYFRPW-YWUHCJSESA-M

InChI=1S/C16H21N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-4,7,9-11,14H,5-6,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7244588 | https://www.ncbi.nlm.nih.gov/pubmed/7191790

Epicillin, a penicillin antibiotic, has never been approved in the USA, however, was studied for the treatment of childhood pneumonia, gonorrhea. Epicillin didn’t show any therapeutic advantages for parenteral treatment over ampicillin. By now, ampicillin remains the best-documented drug.

Approval Year

PubMed

Title	Date	PubMed
Where is the supporting evidence for treating mild to moderate chronic obstructive pulmonary disease exacerbations with antibiotics? A systematic review.	2008-10-10	18847478
Identification of penicillin allergenic determinants that bind IgE antibodies in the sera of subjects with penicillin allergy.	1990-11	1701026

Patents

Sample Use Guides

In Vivo Use Guide

oral dose of epicillin in the treatment of gonorrhoea: (a) 2 g epicillin plus 1 g probenecid, (b) 2 g epicillin alone, (c) 1 g epicillin, 1 g cephradine plus 1 g probenecid, and (d) 1 g epicillin and 1 g cephradine. 11 patients with cholelithiasis and choledocholithiasis: were administered i.v.

Route of Administration: Other

Name

Type

Language

EPICILLIN SODIUM

Common Name

English

EPICILLIN MONOSODIUM

Preferred Name

English

SODIUM EPICILLIN

Common Name

English

Epicillin monosodium [WHO-DD]

Common Name

English

MONOSODIUM EPICILLIN

Common Name

English

4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, 6-((AMINO-1,4-CYCLOHEXADIEN-1-YLACETYL)AMINO)-3,3-DIMETHYL-7-OXO-, MONOSODIUM SALT, (2S-(2.ALPHA.,5.ALPHA.,6.BETA.(S*)))-

Systematic Name

English

Code System Code Type Description

CAS

59446-81-0