Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C16H20N3O4S.Na |
Molecular Weight | 373.402 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CCC=CC3)C([O-])=O
InChI
InChIKey=WQSDWKIPNYFRPW-YWUHCJSESA-M
InChI=1S/C16H21N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-4,7,9-11,14H,5-6,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1
Molecular Formula | Na |
Molecular Weight | 22.9898 |
Charge | 1 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C16H20N3O4S |
Molecular Weight | 350.413 |
Charge | -1 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Epicillin, a penicillin antibiotic, has never been approved in the USA, however, was studied for the treatment of childhood pneumonia, gonorrhea. Epicillin didn’t show any therapeutic advantages for parenteral treatment over ampicillin. By now, ampicillin remains the best-documented drug.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Identification of penicillin allergenic determinants that bind IgE antibodies in the sera of subjects with penicillin allergy. | 1990 Nov |
|
Where is the supporting evidence for treating mild to moderate chronic obstructive pulmonary disease exacerbations with antibiotics? A systematic review. | 2008 Oct 10 |
Patents
Sample Use Guides
oral dose of epicillin in the treatment of gonorrhoea: (a) 2 g epicillin plus 1 g probenecid, (b) 2 g epicillin alone, (c) 1 g epicillin, 1 g cephradine plus 1 g probenecid, and (d) 1 g epicillin and 1 g cephradine.
11 patients with cholelithiasis and choledocholithiasis: were administered i.v.
Route of Administration:
Other
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 18:32:54 GMT 2023
by
admin
on
Sat Dec 16 18:32:54 GMT 2023
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Record UNII |
5F26232JQ8
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Record Status |
Validated (UNII)
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Record Version |
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59446-81-0
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DTXSID60208166
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23722594
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261-765-6
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5F26232JQ8
Created by
admin on Sat Dec 16 18:32:54 GMT 2023 , Edited by admin on Sat Dec 16 18:32:54 GMT 2023
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