U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2Na.O4Se
Molecular Weight 188.94
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM SELENATE

SMILES

[Na+].[Na+].[O-][Se]([O-])(=O)=O

InChI

InChIKey=MHQOTKLEMKRJIR-UHFFFAOYSA-L
InChI=1S/2Na.H2O4Se/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2

HIDE SMILES / InChI

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/24323428 | https://www.ncbi.nlm.nih.gov/pubmed/26468123 | https://www.ncbi.nlm.nih.gov/pubmed/25485856

SELENATE ION is a compound containing an oxoanion with selenium in its highest oxidation state of VI. Selenates are analogous to sulfates and have similar chemistry, but unlike sulfate, selenate is a good oxidizer. Selenate is the form required by organisms that need selenium as a micronutrient. These organisms have the ability to acquire, metabolize and excrete selenium. The level at which selenium becomes toxic varies from species to species and is related to other environmental factors like pH and alkalinity that influence the concentration of selenite over selenate. Selenate and other forms of selenium are highest in areas where ancient seas have evaporated. These areas are enriched in selenium and over millennia, biologic adaptation has occurred.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Effects of trace metal compounds on HIV-1 reverse transcriptase: an in vitro study.
1999 May
Bacterial respiration of arsenic and selenium.
1999 Oct
Patents

Patents

Sample Use Guides

200-400 µg selenium as selenate
Route of Administration: Oral
N2aSW cell viability was detected by the CCK-8 assay. Briefly, N2aSW cells (5X10^3 per well) exposed to sodium selenate at a set of concentrations (0.00001, 0.0001, 0.001, 0.01, 0.1, 1, 10 mmol/L in FBS-free medium) were grown in 96-well-plates for 24 h. 10% CCK-8 reagent was added to each well and the cells were incubated at 37°C for another 2 h. Cells without sodium selenate treatment were used as the control. The absorbance at 450 nm was measured with a reference wavelength of 650 nm by SpecTRA MAX 190 microplate reader (Molecular Devices, Sunnyvale, CA, USA). All experiments were performed in triplicates.
Name Type Language
SODIUM SELENATE
HSDB   MART.   MI   WHO-DD  
Systematic Name English
NSC-378348
Code English
SODIUM SELENATE [MI]
Common Name English
Sodium selenate [WHO-DD]
Common Name English
SODIUM SELENATE [MART.]
Common Name English
SODIUM SELENATE [HSDB]
Common Name English
SELENIC ACID, DISODIUM SALT
Common Name English
SELENIUM (AS SODIUM SELENATE) [VANDF]
Common Name English
DISODIUM SELENATE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C275
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
WHO-VATC QA12CE01
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
EPA PESTICIDE CODE 72002
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
WHO-ATC A12CE01
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
Code System Code Type Description
RXCUI
36717
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY RxNorm
NCI_THESAURUS
C1229
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
FDA UNII
5DQP25600A
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
DRUG CENTRAL
4781
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
MESH
C021747
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
EPA CompTox
DTXSID5032076
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
SMS_ID
100000085993
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
WIKIPEDIA
SODIUM SELENATE
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
MERCK INDEX
m10070
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY Merck Index
DRUG BANK
DBSALT002579
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
CAS
13410-01-0
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PRIMARY
DAILYMED
5DQP25600A
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
PUBCHEM
25960
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
CHEBI
77775
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
ECHA (EC/EINECS)
236-501-8
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
HSDB
6370
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
EVMPD
SUB22098
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
NSC
378348
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY
ChEMBL
CHEMBL2097002
Created by admin on Fri Dec 15 17:16:58 GMT 2023 , Edited by admin on Fri Dec 15 17:16:58 GMT 2023
PRIMARY