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Details

Stereochemistry ACHIRAL
Molecular Formula H2O4Se
Molecular Weight 144.97
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SELENIC ACID

SMILES

O[Se](O)(=O)=O

InChI

InChIKey=QYHFIVBSNOWOCQ-UHFFFAOYSA-N
InChI=1S/H2O4Se/c1-5(2,3)4/h(H2,1,2,3,4)

HIDE SMILES / InChI

Molecular Formula H2O4Se
Molecular Weight 144.97
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/24323428 | https://www.ncbi.nlm.nih.gov/pubmed/26468123 | https://www.ncbi.nlm.nih.gov/pubmed/25485856

SELENATE ION is a compound containing an oxoanion with selenium in its highest oxidation state of VI. Selenates are analogous to sulfates and have similar chemistry, but unlike sulfate, selenate is a good oxidizer. Selenate is the form required by organisms that need selenium as a micronutrient. These organisms have the ability to acquire, metabolize and excrete selenium. The level at which selenium becomes toxic varies from species to species and is related to other environmental factors like pH and alkalinity that influence the concentration of selenite over selenate. Selenate and other forms of selenium are highest in areas where ancient seas have evaporated. These areas are enriched in selenium and over millennia, biologic adaptation has occurred.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Effects of trace metal compounds on HIV-1 reverse transcriptase: an in vitro study.
1999 May
Patents

Patents

Sample Use Guides

200-400 µg selenium as selenate
Route of Administration: Oral
N2aSW cell viability was detected by the CCK-8 assay. Briefly, N2aSW cells (5X10^3 per well) exposed to sodium selenate at a set of concentrations (0.00001, 0.0001, 0.001, 0.01, 0.1, 1, 10 mmol/L in FBS-free medium) were grown in 96-well-plates for 24 h. 10% CCK-8 reagent was added to each well and the cells were incubated at 37°C for another 2 h. Cells without sodium selenate treatment were used as the control. The absorbance at 450 nm was measured with a reference wavelength of 650 nm by SpecTRA MAX 190 microplate reader (Molecular Devices, Sunnyvale, CA, USA). All experiments were performed in triplicates.
Substance Class Chemical
Created
by admin
on Sat Dec 16 03:29:25 UTC 2023
Edited
by admin
on Sat Dec 16 03:29:25 UTC 2023
Record UNII
HV0Y51NC4J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SELENIC ACID
MI  
Systematic Name English
SELENIC ACID [MI]
Common Name English
UN-1905
Code English
UN1905
Code English
Code System Code Type Description
EPA CompTox
DTXSID2064818
Created by admin on Sat Dec 16 03:29:25 UTC 2023 , Edited by admin on Sat Dec 16 03:29:25 UTC 2023
PRIMARY
DRUG BANK
DB11068
Created by admin on Sat Dec 16 03:29:25 UTC 2023 , Edited by admin on Sat Dec 16 03:29:25 UTC 2023
PRIMARY
WIKIPEDIA
SELENIC ACID
Created by admin on Sat Dec 16 03:29:25 UTC 2023 , Edited by admin on Sat Dec 16 03:29:25 UTC 2023
PRIMARY
FDA UNII
HV0Y51NC4J
Created by admin on Sat Dec 16 03:29:25 UTC 2023 , Edited by admin on Sat Dec 16 03:29:25 UTC 2023
PRIMARY
MERCK INDEX
m9836
Created by admin on Sat Dec 16 03:29:25 UTC 2023 , Edited by admin on Sat Dec 16 03:29:25 UTC 2023
PRIMARY Merck Index
CHEBI
18170
Created by admin on Sat Dec 16 03:29:25 UTC 2023 , Edited by admin on Sat Dec 16 03:29:25 UTC 2023
PRIMARY
CAS
7783-08-6
Created by admin on Sat Dec 16 03:29:25 UTC 2023 , Edited by admin on Sat Dec 16 03:29:25 UTC 2023
PRIMARY
PUBCHEM
1089
Created by admin on Sat Dec 16 03:29:25 UTC 2023 , Edited by admin on Sat Dec 16 03:29:25 UTC 2023
PRIMARY
ECHA (EC/EINECS)
231-979-4
Created by admin on Sat Dec 16 03:29:25 UTC 2023 , Edited by admin on Sat Dec 16 03:29:25 UTC 2023
PRIMARY
HSDB
675
Created by admin on Sat Dec 16 03:29:25 UTC 2023 , Edited by admin on Sat Dec 16 03:29:25 UTC 2023
PRIMARY
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