EXEPANOL

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H15NO2
Molecular Weight	193.2423
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of EXEPANOL

Structure Search

SMILES

CN[C@@H]1COC2=C(C=CC=C2)[C@H](O)C1

InChI

InChIKey=JWUPWOYNGNTOKD-WCBMZHEXSA-N

InChI=1S/C11H15NO2/c1-12-8-6-10(13)9-4-2-3-5-11(9)14-7-8/h2-5,8,10,12-13H,6-7H2,1H3/t8-,10+/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8876943 | https://www.ncbi.nlm.nih.gov/pubmed/4039143 | https://www.ncbi.nlm.nih.gov/pubmed/3691640

Exepanol (KC 2450), a benzoxepine derivative, is a gastrokinetic. It facilitated the peristaltic reflex. Exepanol enhances resting pressure of the lower esophageal sphincter.

Approval Year

PubMed

PubMed

Title	Date	PubMed

Patents

Patents

Name

Type

Language

EXEPANOL

Official Name

English

exepanol [INN]

Common Name

English

(±)-CIS-2,3,4,5-TETRAHYDRO-3-(METHYLAMINO)-1-BENZOXEPIN-5-OL

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66880

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

Code System Code Type Description

CAS

77416-65-0

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

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NCI_THESAURUS

C81455

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

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EVMPD

SUB07493MIG

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

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PUBCHEM

71162

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

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FDA UNII

5CF9F84B3A

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

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ChEMBL

CHEMBL2218853

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

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MESH

C045026

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

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SMS_ID

100000081549

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

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INN

5095

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

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EPA CompTox

DTXSID301024600

Created by admin on Fri Dec 15 17:18:44 GMT 2023 , Edited by admin on Fri Dec 15 17:18:44 GMT 2023

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ACTIVE MOIETY

5CF9F84B3A

EXEPANOL