LEMINOPRAZOLE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H23N3OS
Molecular Weight	341.47
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LEMINOPRAZOLE

Structure Search

SMILES

CC(C)CN(C)C1=C(C[S+]([O-])C2=NC3=C(N2)C=CC=C3)C=CC=C1

InChI

InChIKey=PSIREIZGKQBEEO-UHFFFAOYSA-N

InChI=1S/C19H23N3OS/c1-14(2)12-22(3)18-11-7-4-8-15(18)13-24(23)19-20-16-9-5-6-10-17(16)21-19/h4-11,14H,12-13H2,1-3H3,(H,20,21)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8569059 | https://adisinsight.springer.com/drugs/800000604

LEMINOPRAZOLE is an inhibitor of the gastric mucosal proton pump. Its development for the treatment of peptic ulcer was discontinued.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Validity of kissing gastric ulcers induced in rats for screening of antiulcer drugs.	1994	7881021
Effects of NC-1300-O-3 on gastric mucus secretion and prostaglandin release in rats.	1994 Aug	7990269
Effect on gastric mucus of the proton pump inhibitor leminoprazole and its cytoprotective action against ethanol-induced gastric injury in rats.	1994 Jul	7945516

Patents

Patents

Name

Type

Language

LEMINOPRAZOLE

Official Name

English

LEMINOPRAZOLE [JAN]

Common Name

English

NC1300O3

Code

English

NC-1300O3

Code

English

2-(2-(N-ISOBUTYL-N-METHYLAMINO)BENZYLSULFINYL)BENZIMIDAZOLE

Systematic Name

English

BENZENAMINE, 2-((1H-BENZIMIDAZOL-2-YLSULFINYL)METHYL)-N-METHYL-N-(2-METHYLPROPYL)-

Systematic Name

English

(±)-2-((O-(ISOBUTYLMETHYLAMINO)BENZYL)SULFINYL)BENZIMIDAZOLE

Common Name

English

leminoprazole [INN]

Common Name

English

Code System Code Type Description

INN

7002

Created by admin on Sat Dec 16 16:31:44 GMT 2023 , Edited by admin on Sat Dec 16 16:31:44 GMT 2023

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FDA UNII

59H7G93Y1T

Created by admin on Sat Dec 16 16:31:44 GMT 2023 , Edited by admin on Sat Dec 16 16:31:44 GMT 2023

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ChEMBL

CHEMBL2105102

Created by admin on Sat Dec 16 16:31:44 GMT 2023 , Edited by admin on Sat Dec 16 16:31:44 GMT 2023

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SMS_ID

100000082568

Created by admin on Sat Dec 16 16:31:44 GMT 2023 , Edited by admin on Sat Dec 16 16:31:44 GMT 2023

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MESH

C089751

Created by admin on Sat Dec 16 16:31:44 GMT 2023 , Edited by admin on Sat Dec 16 16:31:44 GMT 2023

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CAS

104340-86-5

Created by admin on Sat Dec 16 16:31:44 GMT 2023 , Edited by admin on Sat Dec 16 16:31:44 GMT 2023

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EVMPD

SUB08429MIG

Created by admin on Sat Dec 16 16:31:44 GMT 2023 , Edited by admin on Sat Dec 16 16:31:44 GMT 2023

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PUBCHEM

65881

Created by admin on Sat Dec 16 16:31:44 GMT 2023 , Edited by admin on Sat Dec 16 16:31:44 GMT 2023

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NCI_THESAURUS

C166833

Created by admin on Sat Dec 16 16:31:44 GMT 2023 , Edited by admin on Sat Dec 16 16:31:44 GMT 2023

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ACTIVE MOIETY


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