BOLANDIOL DIPROPIONATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H36O4
Molecular Weight	388.5402
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CC[C@H](OC(=O)CC)[C@@]1(C)CC[C@]3([H])[C@@]4([H])CC[C@H](OC(=O)CC)C=C4CC[C@@]23[H]

InChI

InChIKey=JFAXVZXNIGIDDA-KDWXAGHCSA-N

InChI=1S/C24H36O4/c1-4-22(25)27-16-7-9-17-15(14-16)6-8-19-18(17)12-13-24(3)20(19)10-11-21(24)28-23(26)5-2/h14,16-21H,4-13H2,1-3H3/t16-,17-,18+,19+,20-,21-,24-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://books.google.ru/books?id=uzPwfNYyjjUC&pg=PA1100&redir_esc=y#v=onepage&q&f=false Retrieved from Conservative Management of Sports Injuries By Thomas E. Hyde, Marianne S. Gengenbach, p.1100
Curator's Comment: Description was created based on several sources, including http://www.genome.jp/dbget-bin/www_bget?dr:D01461 and http://www.ncbi.nlm.nih.gov/pubmed/7341343

Bolandiol is an anabolic-androgenic steroid that was never marketed. A dipropionate ester, bolandiol dipropionate (brand names Anabiol, Storinal; former developmental code name SC-7525), has been marketed. Bolandiol dipropionate is an androgen receptor agonist. Research has shown the enhancing effect of Anabiol on hepatocarcinogenesis.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Androgen Receptor 167 Target ID: CHEMBL1871 Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D01461	Agonist 2678

Conditions

Condition	Modality	Targets	Highest Phase	Product
Sports injuries 1 Sources: Hyde, T.E. and Gengenbach, M.S. (2007) Conservative Management of Sports Injuries, page 1100 retrieved from: https://books.google.ru/books?id=uzPwfNYyjjUC	Primary		Approved 8429	Anabiol Approved Use Anabolic steroid
Renal failure 9 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14005420	Primary		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Effect of bolandiol dipropionate (anabiol), an anabolic hormone, on diethylnitrosamine-induced hepatocarcinogenesis in rat.	1981 Dec	7341343
[Various aspects of immunomodulating therapy in patients with protracted pneumonia during convalescence].	1986	3487131

Patents

Sample Use Guides

In Vivo Use Guide

Anabiol was injected at a dose of 5 mg into the thigh muscle at intervals of 2 weeks to rats

Route of Administration: Intramuscular

In Vitro Use Guide

Unknown

Name

Type

Language

BOLANDIOL DIPROPIONATE

Official Name

English

BOLANDIOL DIPROPIONATE [MART.]

Common Name

English

BOLANDIOL DIPROPIONATE [JAN]

Common Name

English

BOLANDIOL DIPROPIONATE [USAN]

Common Name

English

Estr-4-ene-3β,17β-diol dipropionate

Systematic Name

English

SC-7525

Code

English

BOLANDIOL DIPROPIONATE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2360