BOLANDIOL DIPROPIONATE

Possibly Marketed Outside US

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H36O4
Molecular Weight	388.5402
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=C[C@H](CC[C@@H]4[C@H]3CC[C@]12C)OC(=O)CC

InChI

InChIKey=JFAXVZXNIGIDDA-KDWXAGHCSA-N

InChI=1S/C24H36O4/c1-4-22(25)27-16-7-9-17-15(14-16)6-8-19-18(17)12-13-24(3)20(19)10-11-21(24)28-23(26)5-2/h14,16-21H,4-13H2,1-3H3/t16-,17-,18+,19+,20-,21-,24-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C24H36O4
Molecular Weight	388.5402
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	7 / 7
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://books.google.ru/books?id=uzPwfNYyjjUC&pg=PA1100&redir_esc=y#v=onepage&q&f=false Retrieved from Conservative Management of Sports Injuries By Thomas E. Hyde, Marianne S. Gengenbach, p.1100
Curator's Comment: Description was created based on several sources, including http://www.genome.jp/dbget-bin/www_bget?dr:D01461 and http://www.ncbi.nlm.nih.gov/pubmed/7341343

Bolandiol is an anabolic-androgenic steroid that was never marketed. A dipropionate ester, bolandiol dipropionate (brand names Anabiol, Storinal; former developmental code name SC-7525), has been marketed. Bolandiol dipropionate is an androgen receptor agonist. Research has shown the enhancing effect of Anabiol on hepatocarcinogenesis.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Androgen Receptor 169 Target ID: CHEMBL1871 Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D01461	Agonist 2752

Conditions

Condition	Modality	Targets	Highest Phase	Product
Sports injuries 1 Sources: Hyde, T.E. and Gengenbach, M.S. (2007) Conservative Management of Sports Injuries, page 1100 retrieved from: https://books.google.ru/books?id=uzPwfNYyjjUC	Primary		Approved 8583	Anabiol Approved Use Anabolic steroid
Renal failure 9 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14005420	Primary		Basic research	Unknown Approved Use Unknown

Doses

Dose	Population	Adverse events
225 mg 2 times / month multiple, intramuscular Highest studied dose Dose: 225 mg, 2 times / month Route: intramuscular Route: multiple Dose: 225 mg, 2 times / month Sources: https://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/205735/1/ngh033004_831.pdf	unhealthy, ADULT Health Status: unhealthy Age Group: ADULT Sex: M+F Food Status: UNKNOWN Sources: https://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/205735/1/ngh033004_831.pdf	Sources: https://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/205735/1/ngh033004_831.pdf

PubMed

Title	Date	PubMed
[Various aspects of immunomodulating therapy in patients with protracted pneumonia during convalescence].	1986	3487131
Effect of bolandiol dipropionate (anabiol), an anabolic hormone, on diethylnitrosamine-induced hepatocarcinogenesis in rat.	1981-12	7341343

Patents

Sample Use Guides

In Vivo Use Guide

Anabiol was injected at a dose of 5 mg into the thigh muscle at intervals of 2 weeks to rats

Route of Administration: Intramuscular

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:31:40 GMT 2025` Edited by `admin` on `Mon Mar 31 18:31:40 GMT 2025`
Record UNII	595CNE7RHB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BOLANDIOL DIPROPIONATE

Official Name

English

SC-7525

Preferred Name

English

BOLANDIOL DIPROPIONATE [MART.]

Common Name

English

BOLANDIOL DIPROPIONATE [JAN]

Common Name

English

BOLANDIOL DIPROPIONATE [USAN]

Common Name

English

Estr-4-ene-3?,17?-diol dipropionate

Systematic Name

English

BOLANDIOL DIPROPIONATE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2360