Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C15H16O3 |
Molecular Weight | 244.2857 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC(=O)[C@@H](C)C1=CC=C2C=C(OC)C=CC2=C1
InChI
InChIKey=ZFYFBPCRUQZGJE-JTQLQIEISA-N
InChI=1S/C15H16O3/c1-10(15(16)18-3)11-4-5-13-9-14(17-2)7-6-12(13)8-11/h4-10H,1-3H3/t10-/m0/s1
Naproxen methyl ester, a mixture of two isomers R and S, is the precursor of therapeutically important nonsteroidal anti-inflammatory drug naproxen. Naproxen methyl ester can be enantioselectively hydrolyzed by lipases or (S)-enantioselective esterase could catalyze the selective hydrolysis of the (S)-Naproxen methyl ester, giving optically pure (S)-naproxen. In addition, S-naproxen methyl ester is used as a tool for identification and determination of new stereo selective carboxylesterase activities.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: esterase Sso-Est1 from S. solfataricus P1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19544040 |
Conditions
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571OJX4PDN
Created by
admin on Sat Dec 16 08:34:57 GMT 2023 , Edited by admin on Sat Dec 16 08:34:57 GMT 2023
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9899603
Created by
admin on Sat Dec 16 08:34:57 GMT 2023 , Edited by admin on Sat Dec 16 08:34:57 GMT 2023
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DTXSID50180780
Created by
admin on Sat Dec 16 08:34:57 GMT 2023 , Edited by admin on Sat Dec 16 08:34:57 GMT 2023
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26159-35-3
Created by
admin on Sat Dec 16 08:34:57 GMT 2023 , Edited by admin on Sat Dec 16 08:34:57 GMT 2023
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SUBSTANCE RECORD