Details
Stereochemistry | ACHIRAL |
Molecular Formula | K.AsH2O4 |
Molecular Weight | 180.0334 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[K+].O[As](O)([O-])=O
InChI
InChIKey=GVPLVOGUVQAPNJ-UHFFFAOYSA-M
InChI=1S/AsH3O4.K/c2-1(3,4)5;/h(H3,2,3,4,5);/q;+1/p-1
Potassium arsenate is a chemical compound of potassium and arsenic. It is derived from arsenic acid. Arsenic is a chemical element that has the symbol As and atomic number 33. It is a poisonous metalloid that has many allotropic forms: yellow (molecular non-metallic) and several black and grey forms (metalloids) are a few that are seen. Three metalloidal forms of arsenic with different crystal structures are found free in nature (the minerals arsenopyrite and the much rarer arsenolamprite and pararsenolamprite), but it is more commonly found as a compound with other elements. Potassium arsenate is used in the textile, tanning and paper industries, and as an insecticide, especially for fly paper. In medicine arsenic was the preferred treatment for syphilis for many years. It was also thought to treat malaria, leukemia, and chorea. One type of arsenic preparation that became a popular type of patent medicine of the late 1800’s on into the early 1900s’ was Fowler’s solution, which was sold as a treatment for syphilis as well as a general tonic. Fowler’s solution was not a brand of patent medicine but rather a formula containing 1% potassium arsenate, proposed by Thomas Fowler in 1786. Potassium arsenate is toxic and carcinogenic to humans.
Approval Year
PubMed
Title | Date | PubMed |
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Delayed neuronal death after brief histotoxic hypoxia in vitro. | 1995 May |
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Development of an early-tier laboratory bioassay for assessing the impact of orally-active insecticidal compounds on larvae of Coccinella septempunctata (Coleoptera: Coccinellidae). | 2012 Dec |
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Toxicological and biochemical analyses demonstrate no toxic effect of Cry1C and Cry2A to Folsomia candida. | 2015 Oct 23 |
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7722504
The effect of three metabolic inhibitors--iodoacetate, potassium cyanide, and potassium arsenate--on neuronal viability was studied in primary rat cortical and hippocampal CA1 neuronal cultures. Potassium arsenate produced only partial neuronal degeneration, even at a dose of 10 mM.
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Monopotassium arsenate
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232-065-8
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SUBSTANCE RECORD