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Details

Stereochemistry ACHIRAL
Molecular Formula K.AsH2O4
Molecular Weight 180.0334
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of POTASSIUM ARSENATE

SMILES

[K+].O[As](O)([O-])=O

InChI

InChIKey=GVPLVOGUVQAPNJ-UHFFFAOYSA-M
InChI=1S/AsH3O4.K/c2-1(3,4)5;/h(H3,2,3,4,5);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula AsH2O4
Molecular Weight 140.9351
Charge -1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula K
Molecular Weight 39.0983
Charge 1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Potassium arsenate is a chemical compound of potassium and arsenic. It is derived from arsenic acid. Arsenic is a chemical element that has the symbol As and atomic number 33. It is a poisonous metalloid that has many allotropic forms: yellow (molecular non-metallic) and several black and grey forms (metalloids) are a few that are seen. Three metalloidal forms of arsenic with different crystal structures are found free in nature (the minerals arsenopyrite and the much rarer arsenolamprite and pararsenolamprite), but it is more commonly found as a compound with other elements. Potassium arsenate is used in the textile, tanning and paper industries, and as an insecticide, especially for fly paper. In medicine arsenic was the preferred treatment for syphilis for many years. It was also thought to treat malaria, leukemia, and chorea. One type of arsenic preparation that became a popular type of patent medicine of the late 1800’s on into the early 1900s’ was Fowler’s solution, which was sold as a treatment for syphilis as well as a general tonic. Fowler’s solution was not a brand of patent medicine but rather a formula containing 1% potassium arsenate, proposed by Thomas Fowler in 1786. Potassium arsenate is toxic and carcinogenic to humans.

Approval Year

PubMed

Sample Use Guides

In Vivo Use Guide
LD50 Rat oral 14.0 mg/kg
Route of Administration: Oral
In Vitro Use Guide
The effect of three metabolic inhibitors--iodoacetate, potassium cyanide, and potassium arsenate--on neuronal viability was studied in primary rat cortical and hippocampal CA1 neuronal cultures. Potassium arsenate produced only partial neuronal degeneration, even at a dose of 10 mM.
Substance Class Chemical
Record UNII
55K74GS94Q
Record Status Validated (UNII)
Record Version