FENCLORAC

Investigational

Details

Stereochemistry	RACEMIC
Molecular Formula	C14H16Cl2O2
Molecular Weight	287.182
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

OC(=O)C(Cl)C1=CC(Cl)=C(C=C1)C2CCCCC2

InChI

InChIKey=GXEUNRBWEAIPCN-UHFFFAOYSA-N

InChI=1S/C14H16Cl2O2/c15-12-8-10(13(16)14(17)18)6-7-11(12)9-4-2-1-3-5-9/h6-9,13H,1-5H2,(H,17,18)

HIDE SMILES / InChI

Description

Fenclorac is a potent nonsteroidal anti-inflammatory agent with significant analgesic and antipyretic activity. It inhibits prostaglandin synthesis both in vitro and in vivo.

Approval Year

PubMed

PubMed

Show entries

Title	Date	PubMed
The antiphlogistic, antinociceptive and antipyretic properties of fenclorac.	1976 Nov	1008019
Inhibition of the diarrheal and cardiac actions of arachidonic acid by fenclorac, a new anti-inflammatory agent.	1976 Oct 15	994722
Studies on the in vitro inhibition of prostaglandin synthetase by fenclorac (alpha, m-dichloro-p-cyclohexylphenylacetic acid) and indomethacin.	1977 Jun 1	18151

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Name

Type

Language

FENCLORAC

Official Name

English

FENCLORAC [USAN]

Common Name

English

fenclorac [INN]

Common Name

English

Chloro(3-chloro-4-cyclohexylphenyl)acetic acid

Systematic Name

English

WHR-539

Code

English

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Classification Tree

Code System

Code

Nonsteroidal Antiinflammatory Drug

NCI_THESAURUS

C1323

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Code System

Code

Type

Description

MESH

C013530

PRIMARY

EVMPD

SUB07552MIG

PRIMARY

ChEMBL

CHEMBL1614638

PRIMARY

NCI_THESAURUS

C65644

PRIMARY

PUBCHEM

37494

PRIMARY

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ACTIVE MOIETY


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FENCLORAC