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Details

Stereochemistry ACHIRAL
Molecular Formula C19H17NO2
Molecular Weight 291.3438
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NEOCINCHOPHEN

SMILES

CCOC(=O)C1=C2C=C(C)C=CC2=NC(=C1)C3=CC=CC=C3

InChI

InChIKey=BUDBHJPMAKXMLD-UHFFFAOYSA-N
InChI=1S/C19H17NO2/c1-3-22-19(21)16-12-18(14-7-5-4-6-8-14)20-17-10-9-13(2)11-15(16)17/h4-12H,3H2,1-2H3

HIDE SMILES / InChI
Neocinchophen is an analgesic and uricosuric. Cinchophen and neocinchophen (introduced by Chemische Fabrik auf Aktien as Atophan and Novatophan) were being advertised as superior substitutes for salicylates in the treatment of rheumatic fever. Chemically, cinchophen is phenylcinchoninic acid, and neocinchophen is the ethyl ester of its methyl derivative.

Approval Year

Sample Use Guides

Rheumatic fever: Neocinchophen was administered in tablet form, 1 g of the drug being used every hour until definite symptoms of drug action were manifested. The three patients with rheumatic fever that were treated with neocinchophen obtained complete relief from subjective and objective symptoms of the disease after doses of 11, 14 and 16 g. One patient received with impunity 15 g additional to the 11 g, which gave him complete relief.
Route of Administration: Oral
Name Type Language
NEOCINCHOPHEN
INN  
INN  
Official Name English
ETHYL 6-METHYL-2-PHENYL-4-QUINOLINECARBOXYLATE
Systematic Name English
NSC-34910
Code English
neocinchophen [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C241
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
NCI_THESAURUS C921
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
Code System Code Type Description
EVMPD
SUB09194MIG
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY
INN
4159
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY
NCI_THESAURUS
C75068
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY
PUBCHEM
68089
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY
FDA UNII
539M941Y9O
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY
NSC
34910
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY
ChEMBL
CHEMBL1370602
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY
SMS_ID
100000084153
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY
ECHA (EC/EINECS)
207-615-5
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY
EPA CompTox
DTXSID2046250
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY
CAS
485-34-7
Created by admin on Fri Dec 15 16:04:32 GMT 2023 , Edited by admin on Fri Dec 15 16:04:32 GMT 2023
PRIMARY