MESECLAZONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	UNKNOWN
Molecular Formula	C11H10ClNO3
Molecular Weight	239.655
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MESECLAZONE

Structure Search

SMILES

CC1CC2OC3=CC=C(Cl)C=C3C(=O)N2O1

InChI

InChIKey=OJGJQQNLRVNIKE-UHFFFAOYSA-N

InChI=1S/C11H10ClNO3/c1-6-4-10-13(16-6)11(14)8-5-7(12)2-3-9(8)15-10/h2-3,5-6,10H,4H2,1H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4545529 | https://www.ncbi.nlm.nih.gov/pubmed/103240 | https://www.ncbi.nlm.nih.gov/pubmed/6806831

Meseclazone (W-2395) is a non-steroidal anti-inflammatory drug. It exerts anti-inflammatory, analgesic and antipyretic activity. Meseclazone inhibits in vitro and ex vivo platelet aggregation initiated by the release reaction. It inhibits bradykinin-induced bronchospasm.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Effect of meseclazone and other non-steroidal anti-inflammatory drugs on isolated tracheal chain tone.	1979 Jul 1	113226

Name

Type

Language

MESECLAZONE

Official Name

English

meseclazone [INN]

Common Name

English

NSC-297623

Code

English

7-CHLORO-3,3A-DIHYDRO-2-METHYL-2H,9H-ISOXAZOLO(3,2-.BETA.)(1,3)BENZOXAZIN-9-ONE

Common Name

English

2H,9H-ISOXAZOLO(3,2-.BETA.)(1,3)BENZOXACIN-9-ONE, 7-CHLORO-3,3A-DIHYDRO-2-METHYL-

Common Name

English

MESECLAZONE [USAN]

Common Name

English

W-2395

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C257

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

Code System Code Type Description

WIKIPEDIA

Meseclazone

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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NSC

297623

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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INN

4097

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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FDA UNII

51KFT71THG

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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CAS

29053-27-8

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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EVMPD

SUB08783MIG

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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NCI_THESAURUS

C73088

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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ChEMBL

CHEMBL2104738

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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EPA CompTox

DTXSID70865466

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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PUBCHEM

34445

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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SMS_ID

100000081185

Created by admin on Sat Dec 16 17:10:30 GMT 2023 , Edited by admin on Sat Dec 16 17:10:30 GMT 2023

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ACTIVE MOIETY


					51KFT71THG

METABOLITE (PARENT)


					J2YFG68VCZ

5-CHLOROSALICYLIC ACID