DIMECOLONIUM

Details

Stereochemistry	MIXED
Molecular Formula	C14H30N2O2
Molecular Weight	258.4002
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	2

SHOW SMILES / InChI

Structure Search

SMILES

CC1CCCC(C(=O)OCC[N+](C)(C)C)[N+]1(C)C

InChI

InChIKey=ZRPJBDLMSFSJJW-UHFFFAOYSA-N

InChI=1S/C14H30N2O2/c1-12-8-7-9-13(16(12,5)6)14(17)18-11-10-15(2,3)4/h12-13H,7-11H2,1-6H3/q+2

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6154492 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 427, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Dimecolonium is the N-cholinolytic drug. It is the ganglion-blocking agent. The functional activity in some ganglioid neurones increases after administration of various doses of dimecolin during the blockade and after its termination.

Approval Year

Patents

Sample Use Guides

In Vivo Use Guide

Single dose - 10, 30 and 50 mg/kg

Route of Administration: Other

Name

Type

Language

DIMECOLONIUM

Common Name

English

ESTER OF 2-CARBOXY-1,1,6-TRIMETHYLPIPERIDINIUM IODIDE WITH (2-HYDROXYETHYL) TRIMETHYLAMMONIUM

Common Name

English

DIMECOLONIUM CATION

Common Name

English

PIPERIDINIUM, 1,1,2-TRIMETHYL-6-((2-(TRIMETHYLAMMONIO)ETHOXY)CARBONYL)-

Systematic Name

English

DIMECOLONIUM ION

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66886