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Details

Stereochemistry ACHIRAL
Molecular Formula C15H8N2O2
Molecular Weight 248.2362
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRYPTANTHRINE

SMILES

O=C1C2=NC3=C(C=CC=C3)C(=O)N2C4=C1C=CC=C4

InChI

InChIKey=VQQVWGVXDIPORV-UHFFFAOYSA-N
InChI=1S/C15H8N2O2/c18-13-10-6-2-4-8-12(10)17-14(13)16-11-7-3-1-5-9(11)15(17)19/h1-8H

HIDE SMILES / InChI

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Prostaglandin G/H synthase 2
48
Target ID: P35354
Gene ID: 5743.0
Gene Symbol: PTGS2
Target Organism: Homo sapiens (Human)
Inhibitor
8297
Enoyl-[acyl-carrier-protein] reductase [NADH]
1
Target ID: P9WGR1
Gene ID: 886523.0
Gene Symbol: inhA
Target Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Inhibitor
8297
PubMed

PubMed

TitleDatePubMed
Tryptanthrin Analogues as Inhibitors of Enoyl-acyl Carrier Protein Reductase: Activity against Mycobacterium tuberculosis, Toxicity, Modeling of Enzyme Binding.
2019
Name Type Language
TRYPTANTHRINE
Common Name English
TRYPTANTHRIN
Common Name English
INDOLO(2,1-B)QUINAZOLINE-6,12-DIONE
Common Name English
NSC-349447
Code English
TRIPTANTRIN
Common Name English
COUROUPITINE A
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID90157431
Created by admin on Sat Dec 16 12:51:53 GMT 2023 , Edited by admin on Sat Dec 16 12:51:53 GMT 2023
PRIMARY
PUBCHEM
73549
Created by admin on Sat Dec 16 12:51:53 GMT 2023 , Edited by admin on Sat Dec 16 12:51:53 GMT 2023
PRIMARY
NSC
349447
Created by admin on Sat Dec 16 12:51:53 GMT 2023 , Edited by admin on Sat Dec 16 12:51:53 GMT 2023
PRIMARY
FDA UNII
4Y6E3F2U66
Created by admin on Sat Dec 16 12:51:53 GMT 2023 , Edited by admin on Sat Dec 16 12:51:53 GMT 2023
PRIMARY
CAS
13220-57-0
Created by admin on Sat Dec 16 12:51:53 GMT 2023 , Edited by admin on Sat Dec 16 12:51:53 GMT 2023
PRIMARY
SUBSTANCE RECORD
Structure of TRYPTANTHRINE
NIH
NCATS
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