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Details

Stereochemistry ACHIRAL
Molecular Formula C17H19N5
Molecular Weight 293.3663
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ABT-724

SMILES

C(N1CCN(CC1)C2=NC=CC=C2)C3=NC4=CC=CC=C4N3

InChI

InChIKey=FRPJGTNLZNXQEX-UHFFFAOYSA-N
InChI=1S/C17H19N5/c1-2-6-15-14(5-1)19-16(20-15)13-21-9-11-22(12-10-21)17-7-3-4-8-18-17/h1-8H,9-13H2,(H,19,20)

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
12.4 nM [EC50]
PubMed

PubMed

TitleDatePubMed
Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning.
2004 Apr 22
Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction.
2004 Jul 15
Patents
Name Type Language
ABT-724
Common Name English
1H-BENZIMIDAZOLE, 2-((4-(2-PYRIDINYL)-1-PIPERAZINYL)METHYL)-
Systematic Name English
2-((4-(PYRIDIN-2-YL)PIPERAZIN-1-YL)METHYL)-1H-BENZIMIDAZOLE
Systematic Name English
Code System Code Type Description
FDA UNII
4WV2575JWT
Created by admin on Sat Dec 16 09:44:17 GMT 2023 , Edited by admin on Sat Dec 16 09:44:17 GMT 2023
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EPA CompTox
DTXSID001025592
Created by admin on Sat Dec 16 09:44:17 GMT 2023 , Edited by admin on Sat Dec 16 09:44:17 GMT 2023
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CAS
70006-24-5
Created by admin on Sat Dec 16 09:44:17 GMT 2023 , Edited by admin on Sat Dec 16 09:44:17 GMT 2023
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WIKIPEDIA
ABT-724
Created by admin on Sat Dec 16 09:44:17 GMT 2023 , Edited by admin on Sat Dec 16 09:44:17 GMT 2023
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PUBCHEM
5025739
Created by admin on Sat Dec 16 09:44:17 GMT 2023 , Edited by admin on Sat Dec 16 09:44:17 GMT 2023
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