1,1-DIMETHYLHYDRAZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H8N2
Molecular Weight	60.0983
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)N

InChI

InChIKey=RHUYHJGZWVXEHW-UHFFFAOYSA-N

InChI=1S/C2H8N2/c1-4(2)3/h3H2,1-2H3

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Effect of morin on tissue lipid peroxidation and antioxidant status in 1, 2-dimethylhydrazine induced experimental colon carcinogenesis.	2009-02	18496650
Vanadium and 1, 25 (OH)2 vitamin D3 combination in inhibitions of 1,2, dimethylhydrazine-induced rat colon carcinogenesis.	2008-10	18539154
Exercise reduces inflammation and cell proliferation in rat colon carcinogenesis.	2008-04	18317386
Intrinsic denervation of the colon is associated with a decrease of some colonic preneoplastic markers in rats treated with a chemical carcinogen.	2008-04	18297187
Unsymmetrical DMH - an isomer of 1,2 DMH - is it potent to induce gastrointestinal carcinoma in rats?	2008-04	18222660
The metastatic stage-dependent mucosal expression of sialic acid is a potential marker for targeting colon cancer with cationic polymers.	2008-02	17960470
Action of 1,1-dimethylhydrazine on bacterial cells is determined by hydrogen peroxide.	2007-12-01	17869570
Intrinsic resistance to apoptosis of colon epithelial cells is a potential determining factor in the susceptibility of the A/J mouse strain to dimethylhydrazine-induced colon tumorigenesis.	2007-12	17538954
The impact of the pi-electron conjugation on (15)N, (13)C and (1)H NMR chemical shifts in push-pull benzothiazolium salts. Experimental and theoretical study.	2007-11	17924356
Insulin, leptin, and adiponectin receptors in colon: regulation relative to differing body adiposity independent of diet and in response to dimethylhydrazine.	2007-10	17656443
[Effect of ursodeoxycholic acid in an experimental colon cancer model].	2007-09	18052642
[Oxidative metabolism and crystal-forming properties of blood of the experimental animals subjected to nonsymmetrical dimethylhydrazine].	2007-08-29	17722577
Dimethylhydrazine model is not appropriate for evaluating effect of ethanol on colorectal cancer.	2007-08	18020863
Follow-up of tumor development in the colons of living rats and implications for chemoprevention trials: assessment of aspirin-difluoromethylornithine combination.	2007-07	17549408
Entropy effects in the fragmentation of 1,1-dimethylhydrazine ions.	2007-06-28	17539609
[Mutagenic effect of the rocket fuel component asymmetric dimethylhydrazine on rats of various ages].	2007-06	17853800
Mobility resolution and mass analysis of ions from ammonia and hydrazine complexes with ketones formed in air at ambient pressure.	2007-05	17376700
A preliminary assessment of the potential environmental and human health impact of unsymmetrical dimethylhydrazine as a result of space activities.	2007-04	17234248
Direct aldehyde homologation utilized to construct a conjugated-tetraene hydrocarbon insect pheromone.	2007-03-21	17319690
Expression of voltage-gated potassium channels in human and mouse colonic carcinoma.	2007-02-01	17289873
Effect of chronic dietary ethanol consumption on colonic cancer in rats induced by 1,1-dimethylhydrazine.	2007-01	17331170
Total synthesis of (+)-rishirilide B: development and application of general processes for enantioselective oxidative dearomatization of resorcinol derivatives.	2006-12-13	17147370
Synthesis and optical resolution of aminophosphines with axially chiral C(aryl)-N(amine) bonds for use as ligands in asymmetric catalysis.	2006-09-15	16958529
Effect of defunctionalization on colon carcinogenesis in the rat.	2006-09	17092196
The anti-obesity agent Orlistat is associated to increase in colonic preneoplastic markers in rats treated with a chemical carcinogen.	2006-08-28	16377080
Protective role of luteolin in 1,2-dimethylhydrazine induced experimental colon carcinogenesis.	2006-07-20	16850523
Threshold-photoelectron spectroscopic study of methyl-substituted hydrazine compounds.	2006-07-13	16821842
[Human health in the space rocket-making areas: medical and environmental aspects].	2006-07-01	16808395
Trypanosoma cruzi infection and/or administration of the nonsteroidal anti-inflammatory nimesulide increase the number of colonic crypts overexpressing metallothioneins in rat colon carcinogenesis.	2006-07	16862280
Efficacy and tolerability of gemtuzumab ozogamicin (anti-CD33 monoclonal antibody, CMA-676, Mylotarg) in children with relapsed/refractory myeloid leukemia.	2006-06-28	16805911
Chronic colitis promotes tumor development.	2006-06	16685383
Mixed hydrazido amido/imido complexes of tantalum, hafnium and zirconium: potential precursors for metal nitride MOCVD.	2006-01-07	16357967
Development of a biosensor test system with GFP reporter protein for detection of DNA damages.	2006-01	16929958
Zinc hydrazides and alkoxyhydrazides: organometallic compounds with novel Zn4N8, Zn4N6O and Zn4N4O2 cage structures.	2005-12-23	16267868
Effect of oral Lactococcus lactis containing endostatin on 1, 2-dimethylhydrazine-induced colon tumor in rats.	2005-12-14	16437622
Red wine polyphenols influence carcinogenesis, intestinal microflora, oxidative damage and gene expression profiles of colonic mucosa in F344 rats.	2005-12-11	16293270
The enhancing role of vitamin A deficiency on chemically induced nephroblastoma in rats.	2005-12	16338327
Long-lived alphaMUPA transgenic mice show reduced SOD2 expression, enhanced apoptosis and reduced susceptibility to the carcinogen dimethylhydrazine.	2005-12	16139868
Synthesis, structures, and DFT bonding analysis of new titanium hydrazido(2-) complexes.	2005-11-14	16270983
Reactivity of alkynes containing alpha-hydrogen atoms with a triruthenium hydrido carbonyl cluster: alkenyl versus allyl cluster derivatives.	2005-10-07	16052661
Increased susceptibility of vault poly(ADP-ribose) polymerase-deficient mice to carcinogen-induced tumorigenesis.	2005-10-01	16204055
Determination of hydrazine, monomethylhydrazine, 1,1-dimethylhydrazine, and 1,2-dimethylhydrazine by nonaqueous capillary electrophoresis with amperometric detection.	2005-09	16097027
Inositol hexaphosphate-induced enhancement of natural killer cell activity correlates with suppression of colon carcinogenesis in rats.	2005-08-28	16124063
Effect of thalidomide on colorectal cancer liver metastases in CBA mice.	2005-08-01	16028287
Transformed immortalized gastric epithelial cells by virulence factor CagA of Helicobacter pylori through Erk mitogen-activated protein kinase pathway.	2005-06-02	15856031
Influence of the order of reagent addition on NDMA formation during chloramination.	2005-05-15	15952390
A proteomics approach to identify changes in protein profiles in pre-cancerous colon.	2005-04-29	15781235
DNA damage and aberrant crypt foci as putative biomarkers to evaluate the chemopreventive effect of annatto (Bixa orellana L.) in rat colon carcinogenesis.	2005-04-04	15781219
Effect of ethanol consumption on colon cancer in an experimental model.	2005-02	15801884
Biosynthesis of exopolysaccharides by two strains of Lactobacillus bulgaricus in whey-based media.	2001	15954646

Patents

Name

Type

Language

1,1-DIMETHYLHYDRAZINE

Systematic Name

English

NSC-60517

Preferred Name

English

1,1-DIMETHYLHYDRAZINE [MI]

Common Name

English

1,1-DIMETHYLHYDRAZINE [IARC]

Common Name

English

1,1-DIMETHYLHYDRAZINE [HSDB]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C45176