1,1-DIMETHYLHYDRAZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H8N2
Molecular Weight	60.0983
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)N

InChI

InChIKey=RHUYHJGZWVXEHW-UHFFFAOYSA-N

InChI=1S/C2H8N2/c1-4(2)3/h3H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C2H8N2
Molecular Weight	60.0983
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Biosynthesis of exopolysaccharides by two strains of Lactobacillus bulgaricus in whey-based media.	2001	15954646
Dietary copper and dimethylhydrazine affect protein kinase C isozyme protein and mRNA expression and the formation of aberrant crypts in colon of rats.	2001	11673641
Colonic cell proliferation, apoptosis and aberrant crypt foci development in rats given 2-amino-3-methylimidaz.	2001 Apr	11330454
Temporary inactivation of plasma amine oxidase by alkylhydrazines. A combined enzyme/model study implicates cofactor reduction/reoxidation but cofactor deoxygenation and subsequent reoxygenation in the case of hydrazine itself.	2001 Mar 23	11300883
1,1-Dimethylhydrazine.	2002	15323050
Formation of N-nitrosodimethylamine (NDMA) from dimethylamine during chlorination.	2002 Feb 15	11878371
Changes in the microvascular architecture of colorectal liver metastases following the administration of SMANCS/lipiodol.	2002 Mar	11855917
Occupational exposure to hydrazines: treatment of acute central nervous system toxicity.	2003 Dec	14692474
[Pioglitazone, a peroxisome proliferators-activated receptor gamma ligand, inhibits dimethylhydrazine (DMH) induced aberrant crypt foci in rats].	2003 Oct	14601316
Increased expression of the ubiquitin-proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappaB.	2003 Sep 15	12966435
Beef tallow increases apoptosis and decreases aberrant crypt foci formation relative to soybean oil in rat colon.	2004	15572298
Age-related loss of EGF-receptor related protein (ERRP) in the aging colon is a potential risk factor for colon cancer.	2004 Dec	15563939
Titanium hydrazido and imido complexes: synthesis, structure, reactivity, and relevance to alkyne hydroamination.	2004 Feb 18	14871111
Differential protonation and dynamic structure of doxylamine succinate in solution using 1H and 13C NMR.	2004 Jul	15181634
Effect of amaranth leaves on dimethylhydrazine-induced changes in multicomponent antioxidant system of rat liver.	2004 Jun	15260111
Role of lipid-mobilising factor (LMF) in protecting tumour cells from oxidative damage.	2004 Mar 22	15026812
Metal-induced coordination inversion and carbon-nitrogen bond rearrangement. Structurally characterized phenyl isocyanate inserted into aluminum methyl compounds and O- and N-bound aluminum compounds.	2004 Mar 22	15018543
gamma-Hydroxyalkynyl ketones as useful scaffolds for the preparation of combinatorial libraries of furans, isoxazoles and pyrazoles.	2004 May-Jun	15132594
The effect of aspirin and high fibre diet on colorectal carcinoma: a comparative experimental study.	2004 Nov	15655645
[CHL prevent colon neoplasms in mice and its selective inhibition on COX-2].	2004 Nov	15566646
[Protective effect of N-acetylcysteine on acute lung injury caused by exposure to rocket liquid propellant].	2004 Oct	15461841
Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat.	2004 Oct-Dec	15546251
Effect of thalidomide on colorectal cancer liver metastases in CBA mice.	2005 Aug 1	16028287
The enhancing role of vitamin A deficiency on chemically induced nephroblastoma in rats.	2005 Dec	16338327
Dietary exposure to soy or whey proteins alters colonic global gene expression profiles during rat colon tumorigenesis.	2005 Jan 11	15644144
Transformed immortalized gastric epithelial cells by virulence factor CagA of Helicobacter pylori through Erk mitogen-activated protein kinase pathway.	2005 Jun 2	15856031
Influence of the order of reagent addition on NDMA formation during chloramination.	2005 May 15	15952390
Determination of hydrazine, monomethylhydrazine, 1,1-dimethylhydrazine, and 1,2-dimethylhydrazine by nonaqueous capillary electrophoresis with amperometric detection.	2005 Sep	16097027
Entropy effects in the fragmentation of 1,1-dimethylhydrazine ions.	2007 Jun 28	17539609
Mobility resolution and mass analysis of ions from ammonia and hydrazine complexes with ketones formed in air at ambient pressure.	2007 May	17376700
The impact of the pi-electron conjugation on (15)N, (13)C and (1)H NMR chemical shifts in push-pull benzothiazolium salts. Experimental and theoretical study.	2007 Nov	17924356
Insulin, leptin, and adiponectin receptors in colon: regulation relative to differing body adiposity independent of diet and in response to dimethylhydrazine.	2007 Oct	17656443
Unsymmetrical DMH - an isomer of 1,2 DMH - is it potent to induce gastrointestinal carcinoma in rats?	2008 Apr	18222660
Vanadium and 1, 25 (OH)2 vitamin D3 combination in inhibitions of 1,2, dimethylhydrazine-induced rat colon carcinogenesis.	2008 Oct	18539154

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:28:59 GMT 2023` Edited by `admin` on `Fri Dec 15 19:28:59 GMT 2023`
Record UNII	4WPQ90N53J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,1-DIMETHYLHYDRAZINE

Systematic Name

English

1,1-DIMETHYLHYDRAZINE [MI]

Common Name

English

NSC-60517

Code

English

1,1-DIMETHYLHYDRAZINE [IARC]

Common Name

English

1,1-DIMETHYLHYDRAZINE [HSDB]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C45176