Details
Stereochemistry | ACHIRAL |
Molecular Formula | C9H19NO3S |
Molecular Weight | 221.317 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OS(=O)(=O)CCCNC1CCCCC1
InChI
InChIKey=PJWWRFATQTVXHA-UHFFFAOYSA-N
InChI=1S/C9H19NO3S/c11-14(12,13)8-4-7-10-9-5-2-1-3-6-9/h9-10H,1-8H2,(H,11,12,13)
3-(CYCLOHEXYLAMINO)PROPANESULFONIC ACID (CAPS) is a zwitterionic biological buffer which has minimal reactivity with enzymes or proteins and minimal salt effects. CAPS buffer is widely used in Western and immunoblotting experiments as well as protein sequencing and identification. The high pH of this buffer makes it useful for the transfer of proteins with a pI > 8.5. CAPS has been used to study pH-dependent processes in enzymology and as an eluent buffer component in the separation of basic drugs by HPLC.
Approval Year
PubMed
Title | Date | PubMed |
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Expression and prognostic significance of lysozyme in male breast cancer. | 2002 |
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Direct monitoring of the expression of the green fluorescent protein-extracellular signal-regulated kinase 2 fusion protein in transfected cells using capillary electrophoresis with laser-induced fluorescence detection. | 2002 Nov 8 |
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Simultaneous determination of norepinephrine, serotonin, and 5-hydroxyindole-3-acetic acid in microdialysis samples from rat brain by microbore column liquid chromatography with fluorescence detection following derivatization with benzylamine. | 2003 Jan 15 |
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Simultaneous determination of 5-hydroxyindoles and catechols by high-performance liquid chromatography with fluorescence detection following derivatization with benzylamine and 1,2-diphenylethylenediamine. | 2003 Sep 19 |
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Analysis of tryptophan and tyrosine in cerebrospinal fluid by capillary electrophoresis and "ball lens" UV-pulsed laser-induced fluorescence detection. | 2003 Sep 26 |
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Determination of serotonin, noradrenaline, dopamine and their metabolites in rat brain extracts and microdialysis samples by column liquid chromatography with fluorescence detection following derivatization with benzylamine and 1,2-diphenylethylenediamine. | 2004 Aug 5 |
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Fast speciation analysis of iodophenol compounds in river waters by capillary electrophoresis-inductively coupled plasma-mass spectrometry with off-line solid-phase microextraction. | 2004 Jun |
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Oxidative stress in patients with nongenital warts. | 2005 Aug 31 |
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Bishistidyl heme hexacoordination, a key structural property in Drosophila melanogaster hemoglobin. | 2005 Jul 22 |
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Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site. | 2006 |
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Analytical separation of Au/Ag core/shell nanoparticles by capillary electrophoresis. | 2006 Nov 10 |
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On-line enhancement and separation of nanoparticles using capillary electrophoresis. | 2007 Aug 17 |
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Mechanism of proton transfer in the 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni. | 2007 Nov 23 |
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A high-efficiency capillary electrophoresis-based method for characterizing the sizes of Au nanoparticles. | 2007 Oct 12 |
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Identification and characterization of a plastid-localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde detoxification. | 2008 |
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A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion. | 2008 Dec 1 |
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High-affinity IgE receptor-beta chain expression in human mast cells. | 2008 Jul 31 |
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The fungus Neurospora crassa displays telomeric silencing mediated by multiple sirtuins and by methylation of histone H3 lysine 9. | 2008 Nov 3 |
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Stacking enhanced determination of steroids by CE. | 2008 Sep |
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Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate. | 2009 |
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Using micellar electrokinetic chromatography for the highly efficient preconcentration and separation of gold nanoparticles. | 2009 Mar 20 |
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Molecular biosensing mechanisms in the spleen for the removal of aged and damaged red cells from the blood circulation. | 2010 |
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Low aerobic mitochondrial energy metabolism in poorly- or undifferentiated neuroblastoma. | 2010 Apr 19 |
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Biological and structural characterization of a host-adapting amino acid in influenza virus. | 2010 Aug 5 |
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Identification of calcium-binding proteins associated with the human sperm plasma membrane. | 2010 Jan 15 |
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Evaluating binuclear copper(II) complexes for glycoside hydrolysis. | 2010 Mar 15 |
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Rhizobium leguminosarum bv. trifolii rosR is required for interaction with clover, biofilm formation and adaptation to the environment. | 2010 Nov 11 |
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Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease. | 2010 Oct 12 |
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Human primordial germ cell formation is diminished by exposure to environmental toxicants acting through the AHR signaling pathway. | 2010 Sep |
Sample Use Guides
In Vivo Use Guide
Sources: https://chem.nlm.nih.gov/chemidplus/rn/1135-40-6
quail: LD50 oral > 316mg/kg (316mg/kg)
Route of Administration:
Oral
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m3039
Created by
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214-492-1
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CAPS (buffer)
Created by
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70815
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1135-40-6
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DB02219
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DTXSID3061554
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4W981O1LXP
Created by
admin on Sat Dec 16 04:02:32 GMT 2023 , Edited by admin on Sat Dec 16 04:02:32 GMT 2023
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SUBSTANCE RECORD