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Details

Stereochemistry ACHIRAL
Molecular Formula C9H19NO3S
Molecular Weight 221.317
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 3-(CYCLOHEXYLAMINO)PROPANESULFONIC ACID

SMILES

OS(=O)(=O)CCCNC1CCCCC1

InChI

InChIKey=PJWWRFATQTVXHA-UHFFFAOYSA-N
InChI=1S/C9H19NO3S/c11-14(12,13)8-4-7-10-9-5-2-1-3-6-9/h9-10H,1-8H2,(H,11,12,13)

HIDE SMILES / InChI
3-(CYCLOHEXYLAMINO)PROPANESULFONIC ACID (CAPS) is a zwitterionic biological buffer which has minimal reactivity with enzymes or proteins and minimal salt effects. CAPS buffer is widely used in Western and immunoblotting experiments as well as protein sequencing and identification. The high pH of this buffer makes it useful for the transfer of proteins with a pI > 8.5. CAPS has been used to study pH-dependent processes in enzymology and as an eluent buffer component in the separation of basic drugs by HPLC.

Approval Year

PubMed

PubMed

TitleDatePubMed
Expression and prognostic significance of lysozyme in male breast cancer.
2002
Direct monitoring of the expression of the green fluorescent protein-extracellular signal-regulated kinase 2 fusion protein in transfected cells using capillary electrophoresis with laser-induced fluorescence detection.
2002 Nov 8
Analysis of tryptophan and tyrosine in cerebrospinal fluid by capillary electrophoresis and "ball lens" UV-pulsed laser-induced fluorescence detection.
2003 Sep 26
Oxidative stress in patients with nongenital warts.
2005 Aug 31
Chiral ligand exchange micellar electrokinetic chromatography using borate anion as a central ion.
2005 Oct
Changes in endopolygalacturonase levels and characterization of a putative endo-PG gene during fruit softening in peach genotypes with nonmelting and melting flesh fruit phenotypes.
2006
Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine.
2006 Mar 2
On-line enhancement and separation of nanoparticles using capillary electrophoresis.
2007 Aug 17
Identification and characterization of a plastid-localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde detoxification.
2008
A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion.
2008 Dec 1
High-affinity IgE receptor-beta chain expression in human mast cells.
2008 Jul 31
Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate.
2009
Using micellar electrokinetic chromatography for the highly efficient preconcentration and separation of gold nanoparticles.
2009 Mar 20
Molecular biosensing mechanisms in the spleen for the removal of aged and damaged red cells from the blood circulation.
2010
Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins.
2010
Biological and structural characterization of a host-adapting amino acid in influenza virus.
2010 Aug 5
Identification of calcium-binding proteins associated with the human sperm plasma membrane.
2010 Jan 15
Evaluating binuclear copper(II) complexes for glycoside hydrolysis.
2010 Mar 15
Rhizobium leguminosarum bv. trifolii rosR is required for interaction with clover, biofilm formation and adaptation to the environment.
2010 Nov 11
Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease.
2010 Oct 12

Sample Use Guides

quail: LD50 oral > 316mg/kg (316mg/kg)
Route of Administration: Oral
Name Type Language
3-(CYCLOHEXYLAMINO)PROPANESULFONIC ACID
Systematic Name English
CAPS
MI  
Common Name English
3-(CYCLOHEXYLAMINO)-1-PROPANESULFONIC ACID
Systematic Name English
N-CYCLOHEXYL-3-AMINOPROPANESULFONIC ACID
Systematic Name English
WAS-12
Code English
CAPS [MI]
Common Name English
Code System Code Type Description
MERCK INDEX
m3039
Created by admin on Sat Dec 16 04:02:32 GMT 2023 , Edited by admin on Sat Dec 16 04:02:32 GMT 2023
PRIMARY Merck Index
ECHA (EC/EINECS)
214-492-1
Created by admin on Sat Dec 16 04:02:32 GMT 2023 , Edited by admin on Sat Dec 16 04:02:32 GMT 2023
PRIMARY
WIKIPEDIA
CAPS (buffer)
Created by admin on Sat Dec 16 04:02:32 GMT 2023 , Edited by admin on Sat Dec 16 04:02:32 GMT 2023
PRIMARY
PUBCHEM
70815
Created by admin on Sat Dec 16 04:02:32 GMT 2023 , Edited by admin on Sat Dec 16 04:02:32 GMT 2023
PRIMARY
CAS
1135-40-6
Created by admin on Sat Dec 16 04:02:32 GMT 2023 , Edited by admin on Sat Dec 16 04:02:32 GMT 2023
PRIMARY
DRUG BANK
DB02219
Created by admin on Sat Dec 16 04:02:32 GMT 2023 , Edited by admin on Sat Dec 16 04:02:32 GMT 2023
PRIMARY
EPA CompTox
DTXSID3061554
Created by admin on Sat Dec 16 04:02:32 GMT 2023 , Edited by admin on Sat Dec 16 04:02:32 GMT 2023
PRIMARY
FDA UNII
4W981O1LXP
Created by admin on Sat Dec 16 04:02:32 GMT 2023 , Edited by admin on Sat Dec 16 04:02:32 GMT 2023
PRIMARY