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Details

Stereochemistry ACHIRAL
Molecular Formula C12H14NO3
Molecular Weight 220.2445
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of COTARNINIUM

SMILES

COC1=C2OCOC2=CC3=C1C=[N+](C)CC3

InChI

InChIKey=KGZAOSLMBZSSTE-UHFFFAOYSA-N
InChI=1S/C12H14NO3/c1-13-4-3-8-5-10-12(16-7-15-10)11(14-2)9(8)6-13/h5-6H,3-4,7H2,1-2H3/q+1

HIDE SMILES / InChI

Description

Cotarninium is a uterotonic agent. It increases the tone of smooth muscles of internal organs, particularly the uterus. Indicated for the treatment of uterus subinvolution (after childbirth and abortion), dysfunctional uterine bleeding and bleeding due to fibroids and inflammatory processes. Side effects are nausea, allergic reactions. Contraindications are pregnancy and hypersensitivity to the agent.

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
STYPTICIN
Primary
STYPTICIN

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
Subcutaneous: 1 ml of 2-5% solution Topical: Locally 1-2% solution Oral: 50-100 mg 3 times a day
Route of Administration: Other
In Vitro Use Guide
Unknown