4-(2-KETO-1-BENZIMIDAZOLINYL)PIPERIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H15N3O
Molecular Weight	217.267
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 4-(2-KETO-1-BENZIMIDAZOLINYL)PIPERIDINE

SMILES

O=C1NC2=C(C=CC=C2)N1C3CCNCC3

InChI

InChIKey=BYNBAMHAURJNTR-UHFFFAOYSA-N

InChI=1S/C12H15N3O/c16-12-14-10-3-1-2-4-11(10)15(12)9-5-7-13-8-6-9/h1-4,9,13H,5-8H2,(H,14,16)

HIDE SMILES / InChI

Description

4-(2-Keto-1-benzimidazolinyl)piperidine is building block for preparing potent anticancer compounds.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2,596

PubMed

Show entries

Title	Date	PubMed
In vitro inhibition of pimozide N-dealkylation by selective serotonin reuptake inhibitors and azithromycin.	2002 Apr	11910261
Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors.	2005 Mar 15	15745822

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Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Compound (3, 4-(2-Keto-1-benzimidazolinyl)piperidine) activity was evaluated by annexin V/propidium iodide staining-based flow cytometric analysis in human K562 cells after 48h of treatment.

Show entries

Name

Type

Language

R-30507

Preferred Name

English

4-(2-KETO-1-BENZIMIDAZOLINYL)PIPERIDINE

Systematic Name

English

4-(2-OXO-1,3-DIHYDROBENZIMIDAZOL-1-YL)PIPERIDINE

Systematic Name

English

4-(2-OXO-1-BENZIMIDAZOLINYL)PIPERIDINE

Systematic Name

English

1-(4-PIPERIDINYL)-2-BENZIMIDAZOLONE

Systematic Name

English

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Show entries

Code System

Code

Type

Description

FDA UNII

4RP0AED2PC

PRIMARY

CAS

20662-53-7

PRIMARY

ECHA (EC/EINECS)

243-950-3

PRIMARY

EPA CompTox

DTXSID0057679

PRIMARY

PUBCHEM

88638

PRIMARY

Showing 1 to 5 of 5 entries

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PARENT (METABOLITE)


					1HIZ4DL86F

PIMOZIDE

SUBSTANCE RECORD


					4RP0AED2PC

4-(2-KETO-1-BENZIMIDAZOLINYL)PIPERIDINE