PREDNYLIDENE 21-DIETHYLAMINOACETATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C28H39NO6
Molecular Weight	485.6124
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PREDNYLIDENE 21-DIETHYLAMINOACETATE

Structure Search

SMILES

[H][C@@]12CC(=C)[C@](O)(C(=O)COC(=O)CN(CC)CC)[C@@]1(C)C[C@H](O)[C@@]3([H])[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

InChIKey=IFXNTPMREPCLFJ-SLPNHVECSA-N

InChI=1S/C28H39NO6/c1-6-29(7-2)15-24(33)35-16-23(32)28(34)17(3)12-21-20-9-8-18-13-19(30)10-11-26(18,4)25(20)22(31)14-27(21,28)5/h10-11,13,20-22,25,31,34H,3,6-9,12,14-16H2,1-2,4-5H3/t20-,21-,22-,25+,26-,27-,28-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20090326&CC=WO&NR=2009037584A2&KC=A2 | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19920729&CC=EP&NR=0496520A1&KC=A1

Prednisolone 21-diethylaminoacetate, also known as Prednisolamate, is a synthetic corticosteroid used in combination with bronchodilator for treating respiratory disease.

Approval Year

PubMed

Title	Date	PubMed
11beta-hydroxysteroid dehydrogenase types 1 and 2: an important pharmacokinetic determinant for the activity of synthetic mineralo- and glucocorticoids.	2002 Dec	12466373
Transactivation via the human glucocorticoid and mineralocorticoid receptor by therapeutically used steroids in CV-1 cells: a comparison of their glucocorticoid and mineralocorticoid properties.	2004 Sep	15362971
Adalimumab for the treatment of fistulas in patients with Crohn's disease.	2009 Jul	19201775

Patents

Name

Type

Language

PREDNYLIDENE 21-DIETHYLAMINOACETATE

Common Name

English

PREDNYLIDENE DIETHYLAMINOACETATE

Common Name

English

GLYCINE, N,N-DIETHYL-, 21-ESTER WITH 11.BETA.,17,21-TRIHYDROXY-16-METHYLENEPREGNA-1,4-DIENE-3,20-DIONE

Common Name

English

METHYLENEPREDNISOLONE DIETHYLAMINOACETATE

Common Name

English

GLYCINE, N,N-DIETHYL-, (11.BETA.)-11,17-DIHYDROXY-16-METHYLENE-3,20-DIOXOPREGNA-1,4-DIEN-21-YL ESTER

Common Name

English

PREGNA-1,4-DIENE-3,20-DIONE, 11.BETA.,17,21-TRIHYDROXY-16-METHYLENE-, 21-ESTER WITH N,N-DIETHYLGLYCINE

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID501024444

Created by admin on Sat Dec 16 09:06:06 GMT 2023 , Edited by admin on Sat Dec 16 09:06:06 GMT 2023

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PUBCHEM

11496774

Created by admin on Sat Dec 16 09:06:06 GMT 2023 , Edited by admin on Sat Dec 16 09:06:06 GMT 2023

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CAS

6890-42-2

Created by admin on Sat Dec 16 09:06:06 GMT 2023 , Edited by admin on Sat Dec 16 09:06:06 GMT 2023

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FDA UNII

4MII3X430X

Created by admin on Sat Dec 16 09:06:06 GMT 2023 , Edited by admin on Sat Dec 16 09:06:06 GMT 2023

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ACTIVE MOIETY


					IF8PQP966U

PREDNYLIDENE

SUBSTANCE RECORD


					4MII3X430X

PREDNYLIDENE 21-DIETHYLAMINOACETATE