PREDNYLIDENE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H28O5
Molecular Weight	372.4547
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CC(=C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3([H])[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

InChIKey=WSVOMANDJDYYEY-CWNVBEKCSA-N

InChI=1S/C22H28O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-20(13,2)19(15)17(25)10-21(16,3)22(12,27)18(26)11-23/h6-7,9,15-17,19,23,25,27H,1,4-5,8,10-11H2,2-3H3/t15-,16-,17-,19+,20-,21-,22-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C22H28O5
Molecular Weight	372.4547
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	7 / 7
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20090326&CC=WO&NR=2009037584A2&KC=A2 | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19920729&CC=EP&NR=0496520A1&KC=A1

Prednisolone 21-diethylaminoacetate, also known as Prednisolamate, is a synthetic corticosteroid used in combination with bronchodilator for treating respiratory disease.

Approval Year

PubMed

Title	Date	PubMed
11beta-hydroxysteroid dehydrogenase types 1 and 2: an important pharmacokinetic determinant for the activity of synthetic mineralo- and glucocorticoids.	2002 Dec	12466373
Lethal acute respiratory distress syndrome during anti-TNF-alpha therapy for rheumatoid arthritis.	2006 May	16200383
Adalimumab for the treatment of fistulas in patients with Crohn's disease.	2009 Jul	19201775

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:14:55 GMT 2023` Edited by `admin` on `Fri Dec 15 15:14:55 GMT 2023`
Record UNII	IF8PQP966U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PREDNYLIDENE

Official Name

English

METHYLENPREDNISOLONE

Common Name

English

prednylidene [INN]

Common Name

English

PREDNYLIDENE [MART.]

Common Name

English

11.BETA.,17,21-TRIHYDROXY-16-METHYLENEPREGNA-1,4-DIENE-3,20-DIONE

Systematic Name

English

PREDNYLIDENE [MI]

Common Name

English

Prednylidene [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QH02AB11